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There are two ways to interpret/answer this question. First, is there a recognized disorder that is characterized by mania in the absence of depression? Second, are there people who experience mania in the absence of depression? The answer to the first interpretation is no. There is currently no "major manic disorder" or "unipolar mania." Given the DSM-5 ...


Have a look at The God drug DMT. It causes people to see/talk to God and can be taken as an actual drug, but I believe it is also produced in the body during near death experiences. I am no expert in it but here's wikipedia:,N-Dimethyltryptamine

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