Tag Info

Hot answers tagged

6

Most of the 'true' hallucinogens are classified as 5HT2A agonists. 5HT2A is a postsynaptic serotonin receptor. Serotonin-specific reuptake inhibitors (SSRIs) on the other hand act by increasing serotonin (5HT) levels in the brain, which in turn activates presynaptic 5HT1A receptors. Due to a continuous stimulation of these 5HT1A receptors they become ...


5

Human depression has been modeled in a variety of animal models, including cats (Wilner, 1984). Cats show comparable signs of distress when subject to maternal separation, including separation phenomena of protest, followed by despair. Although it is hard to project the DSM-V criteria onto cats, they can show comparable behaviors when subject to anxiety and ...


4

Both schizofrenia and depression are linked to a genetic predisposition and life events. Individuals with no genetic predisposition may become depressed when the trigger is sufficiently intense, while individuals with genetic predisposition may become depressed in the absence of clear life events triggering the depression (Kendler et al, 1995). Reference - ...


4

There is a lot of research on depression in animals. Wikipedia has a good summary of the comparison of depression between animals and humans: It is difficult to develop an animal model that perfectly reproduces the symptoms of depression in patients. Many animals lack self-consciousness, self-reflection, and consideration; moreover, hallmarks of ...


3

I'm not sure about the trained part, but there have been cases where people have spontaneously shifted into a very enjoyable state of mind for a very long time, for example: Eckhart Tolle, who supposedly spent 2 years in utter bliss.


3

It is common for psychological tests to include multiple items with similar meaning. These items are then combined to form an overall scale score (e.g., depression or depressed thoughts). Multiple items with a similar meaning are used to increase the reliability of measurement, which is also important for validity. I don't think there is a huge difference ...


2

Depression is characterized by emotion dysregulation (e.g., Joormann & Vanderlind, 2014). This means that depressed patients have difficulties decreasing (downregulating) their negative affect and increasing (upregulating) their positive affect. This may be a consequence of cognitive distortions and deficits (Joormann & Vanderlind, 2014) as well as ...


2

There's no theoretical reason to believe that depression is characterized by an increase in "double implications." If anything, the double implication you've posed (depression ⟺ no friends) is a pretty accurate understanding of the reciprocal relationship between the causes and consequences of depression (e.g., Stice, Ragan, & Patrick, 2004; Teasdale, ...


2

Dialectical Behavior Therapy (DBT) is a unique skills training that consists of four modules: core mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. Originally, this set of therapeutic skills were developed as treatment for the extremely unmanageable Borderline Personality Disorder. However, after immense success, the ...


2

This is a big question, but here are a few thoughts. While we could argue about the details, concepts around set points and the hedonic treadmill have reasonable empirical support. The general finding is that life satisfaction ratings are fairly stable from year to year (Lucas & Donnellan, 2007) which suggests that there are relatively stable individual ...


2

I would say it is impossible. Beeing unhappy is a necessary experience to make the feeling of happiness arise. Maybe there is some joyful state that can presist over time without unhappiness but i doubt it. As I see it, unhappiness at times comes with the deal of living.


1

I'm no expert on imminent death handling but I have some concepts to share. My suggestions are general suggestions that don't only apply for this scenario but that can be applied more generally, including that scenario. Overcoming fear of death already is not easy, having to do it in an expedited fashion is even more challenging. Fear of death comes from ...


1

You can look into the research being done with ketamine as an amazingly fast antidepressant, even for those with severe treatment resistant depression. Other than that, they now think decreased neurogenesis and synaptogenesis are the more direct and important links to depression. There is also some early research into the links between depression and the ...


1

Two answers: The first, and most important one: do not ask any online forum whether you are getting depressed, since usually there will be many opinions about your situation from people who are not qualified in the field, be it psychiatry or psychotherapy. Please: if you do not feel well, and if your current situation is worrying you, seek help from your ...


1

For "permanent" loss of experience of happiness or pleasure, check out the term Anhedonia From my own understanding, a brain can shift between different states of mind. Depression is just one such state. I have a more detailed answer about states of mind here, but the important point is that states of mind color perception of past, present and future. Your ...


1

In Cognitive Behavioral Therapy, one way to break this cycle is to examine the intensity of the anxiety, or the propensity to think anxiety-inducing thoughts, in different locations, home, shopping, gym, library, movie. Breaking the cycle by limiting time spent in the anxiety-inducing location is beneficial because triggering depression might trigger more ...


1

For a long time now I wanted to write a book on the subject of states of mind. Here are my findings: People are normally prone to experience different states of mind throughout the day. From love to anxiety to anger to creativity. Each one distinctly colors Cognition and affects the outlook on past, present and future. For a certain time only. The state of ...



Only top voted, non community-wiki answers of a minimum length are eligible