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Short answer Mostly Cl- is disregarded in calculations of the resting membrane potential and action potential voltage changes, because it is less important for the neural membrane characteristics than Na+ and K+. Background In some neurons Cl- is not actively transported. In terms of the resting membrane potential, Cl- hence settles its gradient passively ...


In normal neurons, Chloride's reversal potential is near the resting potential for the neuron and also happens to be near the leak conductance reversal potential for the neuron. While not exactly the same these three are sometimes confused. The difference between these three reversal potentials is subtle. Chloride Reversal Potential: is the potential ...

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