For questions about mathematical and computational neuroscience.

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1answer
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What's the functional difference between the NEF and normal ANNs?

Aside from obvious biological plausibility, from a computational standpoint, what's the motivation of using the Neural Engineering Framework (NEF) instead of Artificial Neural Networks (ANNs) for ...
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1answer
49 views

A question on synapses

we are looking into running simulations of the nervous system of C. Elegans. It is believed by most people that the worm's nervous system encodes information through graded potentials and/or plateau ...
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1answer
59 views

How does a human classify or cluster data?

Here, what I mean by DATA are text documents. I am going to do a research on text clustering algorithms by the help of artificial neural networks (ANNs). But first of all I need to know how our brain ...
5
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1answer
257 views

Computational model of biological object recognition

The human brain can achieve a remarkable ability to recognize visual patterns in an Invariant, selective and fast manner. The human visual system is quite powerful. It has an exquisite selectivity ...
5
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1answer
162 views

How long does the trace of a memory last in the brain?

With long-term plasticity one refers to the phenomen by which synapses are modified by neural activity and these modifications last for long times, a day perhaps of the order of days. This phenomenon ...
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2answers
208 views

Measurement of phase difference between two signals using cross correlation vs. fourier transform

I am studying eeg signals with the aim of distinguishing between preictal and interictal epilepsy states based on the eeg signal. I have read some papers and one of the metrics used to distinguish ...
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55 views

How much of brain power consumption is for information

As previously answered on this site, the brain uses 20W of power. However, how much of this power consumption is for information processing and how much of it is for maintenance of biological ...
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0answers
45 views

Why cerebellar input fibers use 2 ways to send a siganl to DCN?

Both groups of input fibers of cerebellum (mossy, climbing) start 2 pathways: 1) project directly to the deep nuclei 2) project to cerebellar cortex, which then (after some processing) sends ...
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42 views

What's the relation between BCM and Oja's learning rule?

A software I'm using has implemented two unsupervised learning algorithms, Oja's and Bienenstock, Cooper, Munro's (BCM) learning rule. I understand that they are two very different algorithms for ...
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33 views

Neurophysiological mappings of empathy

What biologically plausible models are there of empathy? I know there has been a significant amount of work in defining emotion on a neurophysiological basis using models (I'm currently reading this ...
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453 views

What is the difference between computational neuroscience, theoretical neuroscience, and neuroinformatics (if there is one)?

In particular, theoretical and computational neuroscience seem to be synonymous with each other. Neuroinformatics at least seems to deal somewhat more with solving things numerically and the usage and ...
4
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1answer
222 views

Why does optogenetics not mean that perfect brain-computer interfaces are possible?

There have been multiple articles and videos circulating on the Internet claiming that optogenetics has made it possible to have perfect input/output to the brain from a computer. This is obviously ...
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308 views

What are presynaptic puncta?

What are presynaptic puncta? And what makes them different from presynaptic terminals?
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1answer
54 views

What is known about the information that's passed upwards within the neocortex?

The neocortex is likely to process sparse representations in a hierarchy with information close to the raw sensor input appearing in lower levels and abstract concepts being appearing in higher ...
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1answer
59 views

Can dendrite spines fire action potential toward the soma?

I am confused about how the signal propagates from the dendrite spines toward the soma. I believe it is commonly taught that the signal diffuses "passively", i.e. electrostatically with no ...
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1answer
49 views

Does Spaun's serial memory exhibit proactive interference and serial searching

Xuan Choo recentely created a model of serial working memory for Spaun. Does this model of working memory exhibit the effects of proactive interference (as well as changing data types yielding freedom ...
4
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1answer
27 views

Problems with parameterizing neuronal simulation on a limited number of datasets

I'm hoping to contribute to the OpenWorm project by helping their efforts to parameterize the neurons in CElegans so the model elicits biologically realistic behavior. The problem is I've got only ...
4
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1answer
68 views

Is semantic pointer architecture compatible with a predictive coding account of the brain?

Both SPA (Eliasmith et al.) and predictive coding (Friston, Clark, Rao, et al.) seem to have a lot of explanatory power. My understanding of SPA is probably rudimentary, but Eliasmith and others ...
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28 views

Where do spatial dimensions enter in single compartment neuronal models?

I am trying to understand how the length and diameter of a compartment are specified. For example, in the Hodgkin–Huxley model, we only have conductances specified in $\rm mS/cm^2$. How do you specify ...
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33 views

Grating orientation & frequency which induces highest gamma

I am doing some research on perception and gamma activity in V1 area. To check some of my results I need to find an experimental result, from which I would know which orientations and frequencies of ...
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172 views

For binary (spike train) signals, take FFT of signal or autocorrelation of signal?

I want to characterize a binary time-series signal x (derived from neuron action potential data) in the frequency domain. Should I use the FFT of the original signal x, or the power spectrum (FFT of ...
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251 views

Is “Biophysics of Computation” still a good book?

To begin with, I hope this is the right place to ask - if not, please don't be too mad about it :) Currently I'm studying mathematics (2nd year) and I think I'm pretty into neuroscience. To "test" ...
4
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1answer
91 views

Interpretation & Actual Result of “10% of your brain” Myth

It is well known that the common myth that an individual only ever uses 10% of their brain is.. well, a myth. I had a question about a possible interpretation of this idea, and a follow-up question ...
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5answers
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Why do scientists say brains are faster than computers?

Supposing that neurons function similarly to transistors: A neuron able to fire $200$ times per second and transistors can be switched on and off more than $100,000,000,000$ times per second. Let's ...
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4answers
96 views

Can humans be reduced to a function?

Based on an article by UK Essays, we are nothing more than robots that operate based on our past experience and other factors like amount of neurotransmitters, hormones, and other chemicals, trying to ...
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2answers
164 views

Can a biological entity be thought as a simple algorithm? Case-study with the concept of randomness

John Von Neuman believed that all organisms can be though of as information-processing systems. He built on the work of Alan Turing (algorithmic) to create simulations of biological entities. This ...
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2answers
49 views

Color and shape arriving together in visual system

I know that in the visual cortex there are separate visual pathways for both color and shape. Do these separate pathways imply that human beings become consciously aware of these features separately ...
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1answer
93 views

Relation between Nengo, SPA and NEF with respect to other Neural Models

I'm working through How to Build a Brain and I keep getting confused on the relation between Nengo, the Semantic Pointer Architecture (SPA) and the Neurological Engineering Framework (NEF). Are there ...
3
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1answer
205 views

Does the human visual system implement (adaptive) histogram equalization?

The human visual system is very good at 'cancelling out' shadows and other lightning effects, and focusing on the contrast in images. A famous example of this is Adelson's checker shadow illusion: ...
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2answers
23 views

Models relating neuron firing to oscillatory dynamics

Many papers published seem to focused on oscillations to characterize synchronisation and communication between different brain areas. For example, this paper from Voytek et. al where communication ...
3
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1answer
29 views

Publicly Available NEURON models

NEURON is a software package for simulating neurons and networks in great detail. Although it's quite easy to find papers that use NEURON with a simple Google Scholar search, is there some way to find ...
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2answers
56 views

What aspects of ACT-R are not contained within Spaun?

ACT-R was the first big cognitive model and excels at modelling human behavioral data quite accurately. Spaun, which is the world's largest functional brain model, took a lot of ACT-R's insights and ...
3
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2answers
59 views

How do humans learn to combine tasks?

I've been reading about hierarchical learning (a variant of reinforcement learning from what I understand) and how it is shown to allow learning of a higher-level task (the main example is assembly). ...
3
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1answer
55 views

Is there a research field which holds close connections between computational neuroscience and classical robotics

Is there a research field which holds close connections between computational neuroscience and classical robotics, particularly building corresponding robots to implement and test the theories from ...
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1answer
69 views

Neuroscience student [closed]

I'm thinking about studying neuroscience, but the only interests I have in the general area are: Where thought or consciousness come from and how it all works How memory works and why it can't be ...
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1answer
55 views

What are “linear spatial weightings” and “specific temporal windows” in Philiastides & Sajda (2006)?

I am undergraduate student in mathematics and a complete beginner in the field of neuroscience. I recently started a project in Mathematical biology which brought me to the above mentioned paper. I ...
3
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1answer
49 views

Do dissolving myelinated connections explain learning?

In order to understand how we get rid of established habits/behavior: Can myelinated connections be dissolved or are new connections created that bypass those connections?
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2answers
111 views

Neural nets for cognition

I recently got into Neural networks. As much as I have understood, the learning process is based on the change in weights according to stimulus and algorithm used in learning. Does this in any way ...
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1answer
29 views

The article “Vector reconstruction from Firing Rates” of Abbott and Salinas

Is anyone familiar with this article? I am reading it, and it is basically very clear. But still, some points are not clear to me. For example, how is equation (7.1) in page 12: $Q_{i,j}^{-1} = ...
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1answer
20 views

Can anyone see what is wrong with this implementation of the Pinsky-Rinzel model in Brian2?

Not sure if this is the right place to ask this but I've been attempting to implement the Pinsky-Rinzel model in the Brian2 simulator. I'm basing my implementation off the original article here: ...
3
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1answer
24 views

Role of declarative memory in learning skill

In Neil Taatgen's paper on primitive information processing elements (PRIMs) he notes that as a result of saving the used PRIMs in declarative memory (which is fast) as opposed to procedural memory ...
3
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1answer
34 views

Are there theories on how vocabularies for the Semantic Pointer Architecture are created?

The semantic pointer architecture is a vector symbolic architecture where high-dimensional sparse vectors represent concepts. These concepts can be mathematical, linguistic or sensory. In all of the ...
3
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1answer
44 views

How does hPES compare to the learning rates of ANNs?

The primary learning mechanism of artificial neural networks (ANN) is back-propagation, which is not biologically plausible. Trevor Berkolay created an alternative to this learning with the ...
3
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1answer
81 views

link between top-down (bottom-up) processing and cortex layers

What are the relations between top-down and bottom-up processings and the flows of information in the brain? For example, does top-down processing start from some layers and go to lower layers? If so ...
3
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2answers
42 views

Are there models of single neurons on slow timescales?

From what I've come across on the web, most models of single neurons seem to focus on the "fast timescale", where electrical signals are transmitted from one neuron to another. However, neurons are ...
3
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1answer
21 views

How well are neurotransmitters used in SPA?

How much does the SPAUN and the Semantic Pointer Architecture (SPA) that was used to build it take neurotransmitters into account? In the book How to Build a Brain, various inhibitory and excitatory ...
3
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1answer
20 views

How well does the NEF capture neuronal heterogeneity?

From what I understand of the Neurogical Engineering Framework (NEF), groups of neurons are used to compute functions. However, I'm not clear if these calculations take into account neurons of ...
3
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1answer
43 views

How are movements stored in the brain?

The high level flow of information through the brain for the purpose of motor control is well established. It is also known the cerebellum stores many different movements, while also participating in ...
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0answers
27 views

How does the hippocampus and the “Papez” circuit form a memory?

It is admitted the hippocampus is necessary to the formation of new long term memories. At first, information goes back and forth between various parts of the cortex and the hippocampus. That's how a ...
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SaccadeAngular velocity Matlab

I have the data for a monkey's eye position in a cartesian plane synced to the time. I can convert the numbers into polar form however I'm not too sure how to find the angular velocity at that point. ...