1
vote
0answers
7 views

Determining the position of the calcium ion in the three dimensional space

Is it possible to determine the position of a single calcium ion or its population in the context of a three dimensional space with relatively good time frequency, say 1 Hz, taking into account ...
5
votes
2answers
139 views

Why does a neuron choose to connect to another?

I have been reading about neuron creation, guidance cues and all sorts of highly complex mechanisms used to allow one neuron axon to extend or connect - but to what end? Why does one neuron end up ...
0
votes
1answer
34 views

How many action potentials from presynaptic neurons would be required to make a postsynaptic neuron fire?

I am looking for a rough estimation of the number of action potentials from other neurons required to cause a neuron to fire? I read here that a potential of ~ -55mv must be reached before an action ...
1
vote
1answer
28 views

What are the neurobiological factors associated with intelligence in animals?

For example, is there a well-defined relationship between "number of neurons in the cortex" and some measure of "intelligence" in animals? I'm familiar with the encephalization quotient - that is, ...
2
votes
5answers
291 views

Why do scientists say brains are faster than computers?

Supposing that neurons function similarly to transistors: A neuron able to fire $200$ times per second and transistors can be switched on and off more than $100,000,000,000$ times per second. Let's ...
7
votes
1answer
80 views

Importance of Neural Synchrony to Cognition

Is there a consensus on whether computation using Neural Synchrony is reasonable or not? In "How to Build a Brain", Chris Eliasmisth cites Yuko Munakata and R. C. O'Reilly as saying that "the ...
3
votes
1answer
164 views

What is the difference between computational neuroscience, theoretical neuroscience, and neuroinformatics (if there is one)?

In particular, theoretical and computational neuroscience seem to be synonymous with each other. Neuroinformatics at least seems to deal somewhat more with solving things numerically and the usage and ...
2
votes
1answer
97 views

Why does optogenetics not mean that perfect brain-computer interfaces are possible?

There have been multiple articles and videos circulating on the Internet claiming that optogenetics has made it possible to have perfect input/output to the brain from a computer. This is obviously ...
2
votes
1answer
86 views

How do thoughts work at the neuron level?

How does thought work at the biological level of individual neurons? I believe there are many neurons which are active in the brain at the same time. For example, our senses are constantly taking in ...
4
votes
1answer
70 views

What does a cortical column do?

The Blue Brain project led by Henry Markram focused on simulating cortical columns under the idea they form basic processing units of the brain/cognitive function. What does a cortical column do? I ...
6
votes
1answer
78 views

In a central pattern generator based on reciprocal inhibition, how does one “side” get picked over the other to start out?

Consider two neurons, A and B, which reciprocally inhibit each other. If both of the neurons receive input at the same time, it seems to me that no oscillation will occur between the two. Such would ...
8
votes
1answer
85 views

Have there been any mechanisms proposed for normalization in probabilistic population codes?

I heard a talk yesterday by Dora Angelaki about multi-sensory integration. Part of the talk was about bayesian inference with multiple noisy sources of information. I know that there has been a lot ...
2
votes
0answers
204 views

How much information does the somatosensory system produce?

Are there any approximations of how many bits of information human somatosensory system produces? Especially mechano-receptors as measured in average number of bits per area of skin per second? I've ...
5
votes
0answers
96 views

How can I test whether Dorsal Raphe Nucleus(DRN) activity at night is related to variations in mood?

I'm reading this paper, which discusses Serotonin activity in the Dorsal Ralphe Nucleus(DRN), and even includes some mathematical models of how serotonin is released and reabsorbed. The paper states ...
10
votes
1answer
150 views

Computational Model Linking Neural Activity to Behavior

A big question in neuroscience is how neural activity represents knowledge. We can use modelling to explore how different levels of neural activity- subthreshold currents, action potentials, local ...
6
votes
1answer
140 views

Hebbian Learning Rule, Local or Global?

I just learned about the Hebbian Learning Rule. It essentially says "Neurons that fire together, wire together". I'm wondering if the learning rule is affected by the spatial distance of the two ...
7
votes
1answer
100 views

Can processing effort for sub-tasks in neural networks be measured?

I often heard statements like: 80% of your brain processing is computing the effect of gravity or, similarily: You only use 20% of your brain power My question isn't about the truth of ...
10
votes
3answers
382 views

What are the key examples of the use of computational methods in the study of biological neural networks?

In an upcoming postdoc, I'm going to be looking through biological neural network data in the hopes of finding some interesting "patterns". I'm coming at this field from a mathematics/computer ...
18
votes
3answers
893 views

What are current neuronal explanations and models of 'consciousness'?

I would like to understand more about consciousness from a neuroscientific perspective. I have a limited understanding of it in the philosophical/psychological sense through lectures. Although it is ...
8
votes
1answer
115 views

What is the role of traveling waves in circuit formation during cortical development?

Propagating waves of activity have been characterized in various regions of the brain such as the visual cortex (Nauhaus et al., 2012). Recently they have been reported for the first time to occur ...
10
votes
1answer
189 views

What explains variability in the mean firing rate across biological neurons?

Biological neurons have a trade-off between high information transfer (high firing rate) and energy conservation (low firing rate). One would suspect that the maximization of this function has a ...
12
votes
2answers
486 views

Biological plausibility of bayesian models of cognition

Inspired by this question: What are drawbacks to probabilistic models of cognition? I would like to know more about the biological plausibility of Bayesian models of cognition. Is there any neural ...
9
votes
1answer
268 views

How does neural spiking begin in the fetus?

I'm interested in modeling human brain spiking activity. How does the very first spiking activity begin in the fetus? I imagine all spiking activity is initiated by the senses and internal ...
9
votes
2answers
611 views

In what ways can neurons fire randomly?

When developing a model of a biologically-plausible neural network, it is important to know all the circumstances under which neurons can fire. But, I am limiting this question to random firing. In ...
9
votes
1answer
143 views

Is there evidence that STDP is responsible for the ability to infer causation?

Spike timing dependent plasticity (STDP) is a property of synapses that modifies their efficacy based on timing relationships between action potentials in the pre-synaptic and post-synaptic neuron. A ...
22
votes
3answers
12k views

Why would the brain flip the images perceived by your eyes?

The following is a common scientific statement, which you don't have to google long for to find: The eye views images upside-down in the manner of a camera lens, but our brains reinterpret this ...
15
votes
2answers
301 views

How are newly created neurons recruited into existing networks?

As far as I understand, the basics of neurogenesis (abstracted down to the level that makes sense to a computer scientist) is as follows: Neural progenitor cells differentiate into new neurons that ...