For questions about the scientific study of the effects of pharmaceutical and general drugs on perception, behavior, mood and cognition.

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4
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3answers
140 views

Are there any circumstances where schizophrenia or bipolar disorder are not lifelong?

It is known that psychiatric disorders such as schizophrenia and bipolar I, and bipolar II are for life, and require long term treatment (lifelong). Is this always the case? The answer could include ...
5
votes
1answer
67 views

Would administering oxytocin in games of deception improve performance?

As well as facilitating parturition, the hormone oxytocin is thought to mediate "prosocial behaviour" in mammals. It’s been a while since I have read the literature, but I am aware there is robust ...
2
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1answer
83 views

How much sleep is needed for peak cognitive performance?

How much sleep is needed for peak cognitive performance? If some were to, for example, wake up one morning at 12:30PM, would a sleeping pill help obtain better sleep required for that performance the ...
7
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1answer
73 views

What is the Mechanism of 5-HT2A-mediated psychedelia?

Drugs that activate the serotonergic 5-HT2A receptor (e.g. LSD, psilocybin, mescaline) are notorious for causing psychedelic experiences and I would like to know the neurochemical mechanism behind ...
7
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1answer
218 views

Can SSRI make things worse in the long term or cause delayed depression?

I found two articles that mention that taking SSRI for depression can actually make the depression worse. "Now Antidepressant-Induced Chronic Depression Has a Name: Tardive Dysphoria" on Psychology ...
11
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3answers
127 views

Are there any pragmatic uses of hallucinogens?

Hallucinogens (psilocybin, LSD and others) are often regarded as risky substances, therefore they are banned in most places. Are there ways of using these substances that can be beneficial? Or in ...
5
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2answers
67 views

Can hallucinogens treat depressive states?

Given the serotonin hypothesis of depression, increasing synaptic serotonin level may cause anti-depressive effects. Hallucinogens seems to have such advantages: They improve mood at once, but ...
2
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0answers
57 views

What is a short, drug-induced “blackout” experience called?

I know of anecdotal evidence for the following drug-related side-effects: It can happen while getting used to a new drug, or when quitting a drug. Probably also some other situations. The feeling ...
4
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0answers
73 views

Influence of antidepressant drugs upon personality

How do antidepressant drugs influence someone's personality? Do they induce a major change in an individual's personality, or do they just negate the influence of depression? Basically, is the ...
2
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0answers
74 views

What happens inside our body, when we experience betrayal and infidelity?

I guess many of us have experienced it. The moment that you understand that "the person you love, in whom you've trusted, is now with someone else, enjoying every moment with him/her". It's so ...
0
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1answer
145 views

Comprehensive encyclopedia of nootropics for medical researchers and practitioners

Is there a clinically-researched and tested encyclopedia (or similar resource) covering all available nootropics currently known? The Wikipedia article was a helpful first stop; but I'm searching for ...
2
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1answer
361 views

Can the neuronal firing rate be increased through medication/diet?

My rudimentary understanding of the neuronal firing rate is that it varies person to person, and neuron to neuron. So any specific number for a firing rate would be specific to the test subject and ...
10
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4answers
7k views

How to temporarily induce low latent inhibition?

As the Wikipedia article says, High levels of the neurotransmitter dopamine (or its agonists) in the ventral tegmental area of the brain have been shown to decrease latent inhibition. Certain ...
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2answers
239 views

Do smart drugs (nootropics) make you smarter?

Do nootropic drugs like modafinil make you smarter? Are they like coffee?Do they improve working memory?Is there a potential for a pill like NZT-48 from the movie Limitless? From Wikipedia (SPOILER ...
5
votes
1answer
277 views

With the brain's propensity for homeostasis, how can some drugs be labelled addictive and others not?

The human body is always striving for homeostasis. One of the purposes of the brain is to maintain homeostasis, but also the brain needs to maintain homeostasis within itself. Ergo: Given the use of ...
2
votes
1answer
115 views

Why can some drugs make us hallucinate and think the hallucinations are reality?

The question above mainly applies to dramamine. I've only taken 1 tablet for carsickness, but I have read about experiences with that drug. I'm including other drugs that can make you hallucinate and ...
31
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1answer
3k views

Does caffeine improve performance for habituated consumers?

I've seen a fair few studies over the while that suggest caffeine increases arousal in the short term and that for some tasks, this will also increase performance (there's a few citations here). ...
10
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3answers
700 views

Neurotransmitter based imaging techniques

All the brain imaging techniques I know fall into two categories: Tracking blood Either by looking at the magnetic (fMRI), or near-infared absorption (diffuse optical imaging, NIRS) properties of ...
9
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1answer
343 views

Cognitive explanation of why beta blockers are effective for anxiety

Beta blockers essentially reduce physical effects of anxiety and panic disorder, but there is no proof that there is a direct effect on anxiety. Some scientists believe there is an indirect effect. ...