For questions about the biology of the nervous system, from a macroscopic to microscopic perspective.

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9
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1answer
88 views

Are the center surround receptive fields learnt or inherited?

I know that neurons higher in visual pathways can learn their receptive fields after birth, but what about the connections between bipolar cells and Amacarine cells which form center/surround on/off ...
10
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0answers
65 views

What are some known roles or correlations of glucocorticoid receptor function to behaviour?

The NR3C1 gene encodes for a neuron-specific glucocorticoid receptor (GR), of which methylation levels have been shown to relate to altered maternal care and stress response in rodents (Weaver et al., ...
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0answers
175 views

Does data support Domhoff's neurocognitive theory of dreams?

Background: A friend described consistent feelings and themes during a dream. It is my understanding that the contents of our dreams are our subconscious/unconscious/preconscious processing stimuli ...
6
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0answers
58 views

Trying to understand equations in Karl Friston article

I am trying to understand a neuroscience article by Karl Friston. In it he gives three equations that are, as I understand him, equivalent or inter-convertible and refer to both physical and Shannon ...
6
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0answers
117 views

How can I test whether Dorsal Raphe Nucleus(DRN) activity at night is related to variations in mood?

I'm reading this paper, which discusses Serotonin activity in the Dorsal Ralphe Nucleus(DRN), and even includes some mathematical models of how serotonin is released and reabsorbed. The paper states ...
5
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0answers
103 views

What is the neurobiological basis of Spearman general factor of intelligence?

I found here a brief intro to genetic factor of human intelligence: http://www.ncbi.nlm.nih.gov/pubmed/1036362 Also there is known that gyrus hipocampii is basis of STM which have role in general ...
4
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0answers
34 views

How similar are the brains of twins?

I am currently reading undergraduate essays on biological dysfunction and schizophrenia. The students put a lot of weight in the fact that studies of monozygotic twins show only a 50% rate of ...
4
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0answers
33 views

Is there a psychological/physical reason why sometimes your brain won't switch off when you want to sleep?

What is happening to the brain when you are trying to sleep but can't? I think this is a fairly common phenomena. In a situation when you are tired and ready to sleep, why can't you switch off? It's ...
4
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0answers
23 views

Is movement/activity level related to serotonin availability or reuptake rates in the brain?

I'm aware of this research article that explores the relationship between motion and serotonin systems: 5-HT and motor control: a hypothesis. Based on the article above, it seems to me that a "very ...
4
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0answers
36 views

Why does the unilateral 6-OHDA lesion Parkinson's model cause ipsilateral rotations?

As far as I understand, the loss of dopaminergic neurons should hinder movement in the contralateral side of the body, resulting in contralateral rotations when the animal tries to move forward.
4
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0answers
54 views

What is the relationship between topographic maps and sensory memory?

Sensory maps are defined functionally: they exist for a certain time window, are overwritten quickly, are generally inaccessible to introspective control. Topographic maps are defined biologically: ...
4
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0answers
128 views

What are the neurological differences between varying types of love?

It stands to reason that the biochemical cascade involved when a person experiences love, gives a feeling of well-being and drive. Studies in neuroscience have involved chemicals that are present ...
4
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0answers
69 views

What is the neurological mechanism behind the feelings associated with loneliness?

Loneliness can be debilitating, and the feelings associated with it can be overwhelming, including feeling 'cold inside', sad, hopeless and even helpless. Many things can 'cause' loneliness', both ...
4
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0answers
95 views

Is dominance a hypothetical construct or is it based in neurobiology?

There are several personality tests which have dominance as trait or type as result. In addition to this question: How to measure dominance and submissiveness? How are dominant types constructed in ...
4
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0answers
52 views

To what degree does environment govern the severity of symptoms in schizophrenia?

From what I understand about the physiology of schizophrenia it is thought to be caused by chemical imbalances resulting from genetic factors, fueled by environmental factors. I've garnered that ...
3
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0answers
13 views

Classical conditioning paradigm for hippocampal learning

I wanted to know what a suitable classical conditioning experiment would be to analyze learning and memory capabilities in rodent models with respect to hippocampal long-term potentiation. For ...
3
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0answers
13 views

Neurobiology of addiction recovery

While addiction is one of the most studied topics in neurobiology, I don't see very much info on recovery. The information I have found is confusing. This one says striatal DAT bindings return to ...
3
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0answers
77 views

What are the brain regions related to tinnitus shown in this figure?

I am interested in learning about the neural mechanisms behind tinnitus, and was wondering if someone could help me to name the parts of the brain on this image that show increased activity in ...
3
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0answers
59 views

Can positive self-affirmation improve mood?

Most people get "depressed" every now and then - nothing serious, but people sometimes feel down. I am wondering if positive self-affirmation can make you happier by physically increasing the ...
3
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0answers
34 views

Are there parts of the brain which don't change over a lifetime?

We know that during our lifetime the brain develops new neural connections and also there is pruning of neural connections. These phenomena together are called neuroplasticity. Is there any research ...
3
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0answers
44 views

What neurotransmitters can be suppressed/promoted by tDCS

Transcranial Direct Current Stimulation (tDCS) has been shown to modify suppression in the visual cortex and GABA suppression in motor control. As of now, the exact neurobiological mechanism that ...
3
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0answers
32 views

How does neurotransmitter distribution and usage vary thought the brain?

I understand that neurotransmitters are used to send signals between neurons in the brain and that some are used for rather specific functions. However, is the exact ...
3
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0answers
172 views

How does the body experience free-fall during a hypnic jerk

Today I learned that a sudden jerk that you sometimes experience when you are just about to fall asleep due to a sense of free-fall or weightlessness is called a hypnic jerk. If, while sleeping, I ...
3
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0answers
55 views

What regulates the strength of motoric signals?

I've seen cognitive/roboter models where the input signals from the sensors are directly used as the signal for outgoing motoric control. This doesn't make much sense, because obviously we're able ...
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0answers
10 views

Why is the order of white/grey matter different in the brain and spinal cord?

In the brain proper, grey matter forms the outer layer of the brain, and white matter forms the inner layer. In the spine, this is reversed: white matter forms the outer layer of the spine, and grey ...
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0answers
22 views

Have any drugs been shown to increase the neuroplasticity of adult brains?

I read recently in the book "meet your happy chemicals" that the hormones of puberty are neurochemicals that cause your neurons to connect and myelinate more easily. If this is true have any studies ...
2
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0answers
29 views

How can we analyse user behavior to predict urge of smoking?

The problem which I want to target is to be able to successfully predict (to a degree) that a person is going to smoke in near future. I want to look at the relationship between chemical reactions ...
2
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0answers
45 views

How can we use EEG data to predict urge of smoking?

I am from Computer Sciences background. The problem which I want to target is to be able to successfully predict (to a degree) that a person is going to smoke in near future. I have a brainwave ...
2
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0answers
30 views

Physiological mapping of frustration

What physiological changes are seen in the brain when a person is experiencing frustration? What effects do these changes have on learning? Optional background: I'm trying to figure out an ...
2
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0answers
42 views

Can microdialysis be made in Drosophila melanogaster?

Microdialysis is a common method to study the effects of drugs on specific mamal brains zones (mostly in rats), in order to study the it's interaction with the function of those specific areas that ...
2
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0answers
36 views

How do ligands bind to and release from receptors?

I'm wondering exactly how ligands bind to and release from receptors. Until recently I presumed ligands were attracted to receptors through electrostatic forces with no chemical interaction involved, ...
2
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0answers
45 views

Why low audio frequencies seem to detune after an intense workout?

After a specially intense workout (biking, running...), listening to music with headphones, I hear the music pitch has dropped slightly. What I find odd is that not all parts of the sound are detuned, ...
2
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0answers
52 views

Brain structures related to risk-taking behavior

I did a preliminary research on brain structures in which activity might underlie risk-taking behavior. I came to two research that described right prefrontal cortex (Knoch et al., 2006), or ...
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0answers
20 views

Do studies exist that can map specimens of neocortex to the functions they perform(ed) in vivo?

Much brain research has proposed that the brain (the neocortex, esp.) is set up in areas - an area for faces, an area for language, etc.. The experiments typically go 1) damage an area 2) observe ...
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0answers
55 views

What is the result of an excess of dopamine?

I'm pretty familiar with the results of having not enough dopamine, though the reasons are not so clear to me. To get a better insight on the topic I'd like to know something about having too much ...
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0answers
57 views

What are the neurobiological mechanisms behind clumsiness

Some people are inherently clumsy (including your's truly). Everything from frequently stubbing their toes to, as in my case 2 days ago, falling down a single step and managing to crack a rib and ...