For questions about the biology of the nervous system, from a macroscopic to microscopic perspective.

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What are some known roles or correlations of glucocorticoid receptor function to behaviour?

The NR3C1 gene encodes for a neuron-specific glucocorticoid receptor (GR), of which methylation levels have been shown to relate to altered maternal care and stress response in rodents (Weaver et al., ...
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44 views

What exactly is an astroglial calcium wave?

There are quite a few conflicting reports as to what stimulates them, how they propagate, whether they communicate intercellularly, and what they look like. The only consistent information I can ...
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284 views

Does data support Domhoff's neurocognitive theory of dreams?

Background: A friend described consistent feelings and themes during a dream. It is my understanding that the contents of our dreams are our subconscious/unconscious/preconscious processing stimuli ...
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128 views

How can I test whether Dorsal Raphe Nucleus(DRN) activity at night is related to variations in mood?

I'm reading this paper, which discusses Serotonin activity in the Dorsal Ralphe Nucleus(DRN), and even includes some mathematical models of how serotonin is released and reabsorbed. The paper states ...
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51 views

How much of brain power consumption is for information

As previously answered on this site, the brain uses 20W of power. However, how much of this power consumption is for information processing and how much of it is for maintenance of biological ...
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45 views

Why cerebellar input fibers use 2 ways to send a siganl to DCN?

Both groups of input fibers of cerebellum (mossy, climbing) start 2 pathways: 1) project directly to the deep nuclei 2) project to cerebellar cortex, which then (after some processing) sends ...
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35 views

Is movement/activity level related to serotonin availability or reuptake rates in the brain?

I'm aware of this research article that explores the relationship between motion and serotonin systems: 5-HT and motor control: a hypothesis. Based on the article above, it seems to me that a "very ...
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116 views

What is the neurobiological basis of Spearman general factor of intelligence?

I found here a brief intro to genetic factor of human intelligence: http://www.ncbi.nlm.nih.gov/pubmed/1036362 Also there is known that gyrus hipocampii is basis of STM which have role in general ...
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167 views

What are the neurological differences between varying types of love?

It stands to reason that the biochemical cascade involved when a person experiences love, gives a feeling of well-being and drive. Studies in neuroscience have involved chemicals that are present ...
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77 views

What is the neurological mechanism behind the feelings associated with loneliness?

Loneliness can be debilitating, and the feelings associated with it can be overwhelming, including feeling 'cold inside', sad, hopeless and even helpless. Many things can 'cause' loneliness', both ...
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62 views

To what degree does environment govern the severity of symptoms in schizophrenia?

From what I understand about the physiology of schizophrenia it is thought to be caused by chemical imbalances resulting from genetic factors, fueled by environmental factors. I've garnered that ...
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25 views

How separate are the left and right hemisphere vasculature?

It appears as if there are communicating arteries between the right and left hemispheres of the brain, but it is difficult to grasp the larger picture. To what extent is the blood supply to each ...
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53 views

very weird Split Brain Dual Consciousness experiments references on Wikipedia

I have been reading about the problem of possible dual consciousness in split brain patients and I came across this wikipedia page about: ...
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30 views

How are psychological bio-markers discovered?

Recently, this paper claiming to be able to distinguish bipolar disorder from major depressive disorder via a urine sample has come to my attention. Despite reading the paper, I'm unable to ...
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46 views

What personality traits correlate with estrogen?

I'm looking for psychological traits that are proved to correlate with estrogen levels. Anything of specific behavior, attitudes, life styles, emotions, preferences, you name it. (I'm looking for ...
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38 views

How does oxygen deprivation affect neural activity?

It is increasingly common for someone to regain a heartbeat after a cardiac arrest. During the time that the person is without a heartbeat, and so without circulation, the brain is deprived of oxygen. ...
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87 views

Have any drugs been shown to increase the neuroplasticity of adult brains?

I read recently in the book "meet your happy chemicals" that the hormones of puberty are neurochemicals that cause your neurons to connect and myelinate more easily. If this is true have any studies ...
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44 views

Why does the unilateral 6-OHDA lesion Parkinson's model cause ipsilateral rotations?

As far as I understand, the loss of dopaminergic neurons should hinder movement in the contralateral side of the body, resulting in contralateral rotations when the animal tries to move forward.
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61 views

What is the relationship between topographic maps and sensory memory?

Sensory maps are defined functionally: they exist for a certain time window, are overwritten quickly, are generally inaccessible to introspective control. Topographic maps are defined biologically: ...
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98 views

Is dominance a hypothetical construct or is it based in neurobiology?

There are several personality tests which have dominance as trait or type as result. In addition to this question: How to measure dominance and submissiveness? How are dominant types constructed in ...
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58 views

What regulates the strength of motoric signals?

I've seen cognitive/roboter models where the input signals from the sensors are directly used as the signal for outgoing motoric control. This doesn't make much sense, because obviously we're able ...
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30 views

Infants tend to look longer at novel stimuli than at repeated stimuli, is this true in adults?

I have recently read an article in which it is stated, that the researchers can discriminate if a baby knows an object, by looking at the length of time the baby looks at the object. Do adults also ...
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37 views

Neurotransmitter detection in the brain

How are the effects of drugs in the brain, in terms of neurotransmitters measured? For example, Selective Seretonin Reuptake Inhibitors are a class of anti-depressants. How was and is this type of ...
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41 views

Is the fight or flight response considered voluntarily or involuntarily?

I look in my rearview and see someone feet from me still speeding up and my heart rate feels like it doubles. It stayed like that for an hour. Had troubles concentrating and working well into the ...
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112 views

What are the brain regions related to tinnitus shown in this figure?

I am interested in learning about the neural mechanisms behind tinnitus, and was wondering if someone could help me to name the parts of the brain on this image that show increased activity in ...
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44 views

Are there parts of the brain which don't change over a lifetime?

We know that during our lifetime the brain develops new neural connections and also there is pruning of neural connections. These phenomena together are called neuroplasticity. Is there any research ...
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48 views

What neurotransmitters can be suppressed/promoted by tDCS

Transcranial Direct Current Stimulation (tDCS) has been shown to modify suppression in the visual cortex and GABA suppression in motor control. As of now, the exact neurobiological mechanism that ...
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42 views

Physiological mapping of frustration

What physiological changes are seen in the brain when a person is experiencing frustration? What effects do these changes have on learning? Optional background: I'm trying to figure out an ...
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45 views

How does neurotransmitter distribution and usage vary thought the brain?

I understand that neurotransmitters are used to send signals between neurons in the brain and that some are used for rather specific functions. However, is the exact ...
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0answers
44 views

Can microdialysis be made in Drosophila melanogaster?

Microdialysis is a common method to study the effects of drugs on specific mamal brains zones (mostly in rats), in order to study the it's interaction with the function of those specific areas that ...
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212 views

How does the body experience free-fall during a hypnic jerk

Today I learned that a sudden jerk that you sometimes experience when you are just about to fall asleep due to a sense of free-fall or weightlessness is called a hypnic jerk. If, while sleeping, I ...
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11 views

Is there a disorder that causes one to feel heat from an inanimate object?

We just met a woman that feels heat (literally, hot enough for her to say she was burned) from inanimate objects. She says it is mainly the floors and chairs in her home, and she is unable to walk in ...
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35 views

Source of sensory data related to cognitive effort

How does the brain assess cognitive effort? Is there a chemical that is being created or consumed at a rate that is proportionate to the amount of effort felt? I'm mostly interested in short term ...
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20 views

How common is it for twins conjoined at the head to share thoughts and visual stimuli?

I've always been interested in the possibility of a pair of conjoined twins, joined at the head, being able to read each other's thoughts, react to stimuli that one of them can't see/hear/feel, and ...
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25 views

Do studies exist that can map specimens of neocortex to the functions they perform(ed) in vivo?

Much brain research has proposed that the brain (the neocortex, esp.) is set up in areas - an area for faces, an area for language, etc.. The experiments typically go 1) damage an area 2) observe ...
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31 views

How can we analyse user behavior to predict urge of smoking?

The problem which I want to target is to be able to successfully predict (to a degree) that a person is going to smoke in near future. I want to look at the relationship between chemical reactions ...
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57 views

How can we use EEG data to predict urge of smoking?

I am from Computer Sciences background. The problem which I want to target is to be able to successfully predict (to a degree) that a person is going to smoke in near future. I have a brainwave ...
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0answers
48 views

How do ligands bind to and release from receptors?

I'm wondering exactly how ligands bind to and release from receptors. Until recently I presumed ligands were attracted to receptors through electrostatic forces with no chemical interaction involved, ...
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49 views

Why low audio frequencies seem to detune after an intense workout?

After a specially intense workout (biking, running...), listening to music with headphones, I hear the music pitch has dropped slightly. What I find odd is that not all parts of the sound are detuned, ...
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0answers
55 views

Brain structures related to risk-taking behavior

I did a preliminary research on brain structures in which activity might underlie risk-taking behavior. I came to two research that described right prefrontal cortex (Knoch et al., 2006), or ...
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24 views

When we say signals go from one cortical area to an other one do we mean they go directly without going through the thalamus for example?

Or is it implied signals always have to go back and forth between the thalamus and the cortex? Or is it possible they do both at the same time? Or maybe for areas next to each others they can go ...
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6 views

How can higher concepts get unrolled with upward and feedback connections differing?

In the neocortex, input patterns are compressed hierarchically. Sensory inputs in the lower levels are combined by higher levels to form abstract concepts. However, there are even more feedback ...
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16 views

Where can I find good references about the neuronal connections in various areas in the cortex?

As an example, I would like to know which Brodmann areas the layer IV in area 10 receives input from. To which degree are these connections known? What are good books or other kinds of resources that ...
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25 views

How to write a neuroscience research abstract?

I might have to start working on a research abstract for college soon, and I am looking for basic tips on beginning one. I don't mean information about the research specifically; I simply mean ...
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30 views

What is the importance of Dissociation (Both Double/Single) in a Distributed Hierarchical Organisational model of brain function?

How does Dissociation fir with a Hierarchical Organisational model Like Luria's or Distributed model of Fellman & Van Essen? Also, how may patients do you think should be the minimal amount in ...
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61 views

What are the neurobiological mechanisms behind clumsiness

Some people are inherently clumsy (including your's truly). Everything from frequently stubbing their toes to, as in my case 2 days ago, falling down a single step and managing to crack a rib and ...
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0answers
8 views

Do gating mechanisms in the neocortex have individual degrees for all gated connections?

For example, the upward connection between layers in the neocortex flows through the Thalamus which is assumed to have a gating function. I wonder whether there is a single value per gate, ...
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11 views

What causes dopamine in our body

I was curious as to know what are the natural causes for the secretion of dopamine in our body. Are there any specific foods that increases the dopamine level? It is said that dopamine are usually ...
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what is the exact definition of a receptive field ?

i have read the wikipedia article on receptive fields . the article defines a receptive field as The receptive field of an individual sensory neuron is the particular region of the sensory space ...
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11 views

location of the center surround receptive fields for retinal ganglion cells

i have read wikipedia article about receptive fields of visual system . it says The receptive field is often identified as the region of the retina where the action of light alters the firing of ...