For questions about the biology of the nervous system, from a macroscopic to microscopic perspective.

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Perforated patches: Can antibiotics used to induce holes in membrane produce perforations of differential size?

Perforated patches are a special type of patch clamping. I understand that it is sometimes preferred to whole-cell recordings because it prevents complete diffusion of the electrode solution into the ...
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2answers
79 views

Can repetitive sports-related head injuries make a person senile many years later?

Would repetitive football injuries to the cranium show up decades later, causing symptoms resembling mild retardation, OCD, etc.? What is the best way to determine this in terms of imaging, testing, ...
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22 views

How do ligands bind to and release from receptors?

I'm wondering exactly how ligands bind to and release from receptors. Until recently I presumed ligands were attracted to receptors through electrostatic forces with no chemical interaction involved, ...
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42 views

Why low audio frequencies seem to detune after an intense workout?

After a specially intense workout (biking, running...), listening to music with headphones, I hear the music pitch has dropped slightly. What I find odd is that not all parts of the sound are detuned, ...
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70 views

Can “7 deadly sins/virtues” be explained in terms of brain hormone level or receptor mutations? [closed]

I'm thinking about this question on biology.se: do hormones make men think of sex? From the interview linked in the answer, I get two takeaways: a man who lost most testosterone for 4 months ...
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206 views

How much information does the somatosensory system produce?

Are there any approximations of how many bits of information human somatosensory system produces? Especially mechano-receptors as measured in average number of bits per area of skin per second? I've ...
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0answers
135 views

Is happiness a result of cognitive or a side effect of neurobiological processes? [closed]

This morning I've heard this talk on Ted.com: Matt Killingsworth: Want to be happier? Stay in the moment The presenter is discussing an iPhone app used to track happiness, and seems to draw a ...
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0answers
239 views

Are end-stage Alzheimer's patients still conscious? [closed]

I asked the same question at Reddit here, but none of the responses were convincing. So here's the thing: to the extent of what we know about consciousness, are end-stage Alzheimer's patients still ...
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1answer
142 views

How does the body experience free-fall during a hypnic jerk

Today I learned that a sudden jerk that you sometimes experience when you are just about to fall asleep due to a sense of free-fall or weightlessness is called a hypnic jerk. If, while sleeping, I ...
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8answers
1k views

What's the major difference between mind and brain?

I am preparing a presentation on "Mind Reading Computer", and all articles that I came across were focused on reading interpretations from brain through sensors. Articles like this clearly show a ...
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2answers
70 views

What background is required to understand the book “Principles of Neural Science”?

What is the necessary background to read this book and comprehend it? I've taken Calc I-II, Chem 1A and Bio 1A. Is this enough?
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1answer
131 views

Can the neuronal firing rate be increased through medication/diet?

My rudimentary understanding of the neuronal firing rate is that it varies person to person, and neuron to neuron. So any specific number for a firing rate would be specific to the test subject and ...
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1answer
60 views

Is there another example of a strongly emergent phenomenon besides the mind?

If you agree that the mind arises from the brain and is an emergent property of it, then the mind has to be strongly emergent, rather than weakly emergent. Is there any other example in reality of a ...
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1answer
320 views

Studies linking brain chemistry to sexual infidelity

This study Oxytocin Modulates Social Distance between Males and Females examines the effects of Oxytocin (OXT) on men in monogamous relationships. It demonstrates that OXT assists in maintaining ...
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1answer
28 views

What are the neurobiological factors associated with intelligence in animals?

For example, is there a well-defined relationship between "number of neurons in the cortex" and some measure of "intelligence" in animals? I'm familiar with the encephalization quotient - that is, ...
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1answer
70 views

Brain after (electrical) blackout

I was wondering what happens if we lose all electrical impulses in our nervous system for a minimum amount of time. So first of all it is obvious that we will break together, as we are dead while we ...
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1answer
56 views

Law and its formula that says: more time organism working the slower (or less precise) the movements

What is the name of the law and the equation that says that "the more time an organism is working the slower (or less precise) its movements." ? I read once that there is a law in behavioral science ...
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2answers
82 views

How to make diagnosis of these symptoms using Pet scan, fMRI, and EEG?

The symptoms are muscle weakness, slow reaction time, visual perception issues, seizures, hearing loss, weight gain, general sense of pain and delusions. Using the above scanning techniques, a doctor ...
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1answer
59 views

Evolutionary motivation for the existence of pleasure

Firstly, I'd like to understand, what exactly is pleasure? If we presume we are streams of thoughts, thoughts being neurons activated in some pattern, and that basically anything what the conscience ...
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2answers
53 views

Are there any serious neuroscientific theories of emotional valence?

Could anyone tell me if there are any serious neuroscientific mechanisms that have been proposed to explain how feelings of body states take on a positive or negative character (valence)? An example ...
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1answer
41 views

What is the current consensus on if fMRI studies in blood flow actually match brain activity?

How good is blood flow (BOLD signal) as a measure of actual neural activity? What deficiencies exist?
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1answer
87 views

How does the brain learn abstract maths?

I have found quite a bit of information of how, on a neurological level, we learn the most basic forms of maths. We seem to be hardwired from the get go, to deal with manageable quantities, can ...
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0answers
17 views

Physiological mapping of frustration

What physiological changes are seen in the brain when a person is experiencing frustration? What effects do these changes have on learning? Optional background: I'm trying to figure out an ...
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0answers
18 views

What is the neurobiological difference between Jungian Judging and Perceiving individual?

Jungian or Myers Briggs type indicator reserves the last letter of a 4 letter archetype to stand for Judging or Perceiving. Part of being a Judging type is punctuality - being on time, keeping ...
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0answers
24 views

What ways can STEM teaching change in USA to accommodate social needs of females?

Brizendine seems to point to the female brain as a handicap for STEM education due to the typical female's need for communication and sociability because of their estrogen needs eschew solitary ...
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0answers
8 views

Determining the position of the calcium ion in the three dimensional space

Is it possible to determine the position of a single calcium ion or its population in the context of a three dimensional space with relatively good time frequency, say 1 Hz, taking into account ...
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0answers
36 views

Can microdialysis be made in Drosophila melanogaster?

Microdialysis is a common method to study the effects of drugs on specific mamal brains zones (mostly in rats), in order to study the it's interaction with the function of those specific areas that ...
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76 views

Is there a correlation between brain size and amount of sleep?

As far as we know, sleep seems to be the part of the daily cycle when executive functions are resting and memories are fortifying. Many, but not all, of the functions that become dysfunctional upon ...
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49 views

Brain structures related to risk-taking behavior

I did a preliminary research on brain structures in which activity might underlie risk-taking behavior. I came to two research that described right prefrontal cortex (Knoch et al., 2006), or ...
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0answers
26 views

Do our brains have difficulties detecting no?

In most business seminars, or in movie the secret, for example, it is said that if we want to be rich we need to believe we want to be rich. We got to want peace, not anti war. We got to be pro ...
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0answers
67 views

Are our brains just energy conserving systems? [closed]

Is the brain a purely energy conserving system that creates behaviours for conserving the energy distributed to the brain, based on the input of sensory information that our bodies take in?
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0answers
52 views

What are the neurobiological mechanisms behind clumsiness

Some people are inherently clumsy (including your's truly). Everything from frequently stubbing their toes to, as in my case 2 days ago, falling down a single step and managing to crack a rib and ...
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0answers
354 views

What is a good beginner level book on neuroanatomy? [closed]

I'm looking for a beginner level book on neuroanatomy. I haven't any background in neuroanatomy, other than what I learnt back at school. I'd like to take up a post grad neuroscience course to help ...
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1answer
121 views

Where do our memories get stored and how are they retrieved again?

In one of Karl Lashley's 1950 papers, it is pointed out that information is not stored locally in certain area of the brain. Instead, it's stored distributively over the structure of the brain. I'm ...
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2answers
118 views

Where do our memories get stored and how are they retrieved again?

There is a common knowledge that several brain areas are involved in memory processes and each area is involved in a different aspect of memory. But where do our memories get stored and how are they ...
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1answer
136 views

How many calories do we burn when we try to understand mathematical proofs?

While thinking we burn calories. For comparison: "And if it’s the right wood and the right chess grand masters in the middle of a tournament, they are going through 6,000 to 7,000 calories a day ...
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1answer
35 views

How many action potentials from presynaptic neurons would be required to make a postsynaptic neuron fire?

I am looking for a rough estimation of the number of action potentials from other neurons required to cause a neuron to fire? I read here that a potential of ~ -55mv must be reached before an action ...
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1answer
25 views

The function of pumps in forming the resting potential

I am confused by the following. Apparently the resting potential of -65mV is reached when the two forces, diffusion and electrical gradient are in equilibrium. So why does the book say "The ...
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0answers
15 views

How to start learning neuroscience? [closed]

I'm transhumanism enthusiast and I want to learn more about neuroscience, especially about brain-computer interface concept and how it works. How can I start learning? Can you point me to some online ...
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0answers
14 views

What chemical or neurological mechanism causes the feeling of fulfillment?

We all know that someone can find intense pleasure in something without finding it fulfilling. But what causes our feeling of fulfillment? If I knew what it was, I could be more fulfilled and ...
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0answers
37 views

What is the result of an excess of dopamine?

I'm pretty familiar with the results of having not enough dopamine, though the reasons are not so clear to me. To get a better insight on the topic I'd like to know something about having too much ...
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28 views

How to calculate the magnitude of the potential that will develop across the membrane?

If a cell is only permeable to K+ the inside of the cell is at 100mM KCL and outside at 1mM KCL What is the magnitude of the potential that will develop across the membrane?
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25 views

Do all humans have some amount of prions?

I understand that some humans can have prions that develop into neural diseases, but do all of us have at least some amount of prions in our bodies, and more specifically our brains?
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2answers
106 views

Why do we have so many wishes and desires?

Two years ago I started to learn (as self-education) evolution theory and neurobiology for to understand - who we are and where we came from? Now I see clearly that we are our brains, which are the ...
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1answer
45 views

How exactly does alcohol consumption damage dendrites?

How exactly does alcohol consumption damage dendrites? I'm not talking about over a long period of usage, but just one instance.
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28 views

Do people with prenatal hyperkinetic dysfunction have better endurace?

I have a question about hyperkinetic dysfunction. I wonder if theres a relation between HKD and the physical fitness, like endurance or strength, because I have a case, where someone never does ...
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39 views

Is the Orch-OR Penrose-Hameroff model for consciousness sensible? [duplicate]

I would definitely consider myself a fan of Penrose, but I know very little about Hameroff. My questions, basically, are: Do you think that the theory seems sensible and well based? Why do you ...
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103 views

Is Brain Sync music effective in increasing cognitive functioning?

From the website: BRAIN SYNC meditation CDs and guided imagery techniques are proven to significantly improve mental performance. In two decades, nearly 3 million Brain Sync users have ...
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0answers
59 views

Has a Split Brain patient's right brain been asked if he has qualia?

For split brain patients, usually only the left brain is capable of language and thus deep communication is done only with that part. However, some split brain patients have a more or less language ...
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1answer
406 views

Do people feel emotions less strongly as they grow older? [closed]

I'm specifically interested in whether or not their maximum ability to feel an emotion decreases as they grow older (so by that I'm meaning - let's ignore the effects of tolerance induced by life ...