For questions about the biology of the nervous system, from a macroscopic to microscopic perspective.

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How does oxygen deprivation affect neural activity?

It is increasingly common for someone to regain a heartbeat after a cardiac arrest. During the time that the person is without a heartbeat, and so without circulation, the brain is deprived of oxygen. ...
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0answers
53 views

What exactly is an astroglial calcium wave?

There are quite a few conflicting reports as to what stimulates them, how they propagate, whether they communicate intercellularly, and what they look like. The only consistent information I can ...
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4answers
205 views

If a human brain would be placed inside that of an animal: Could it talk?

Assumption: Animals can't talk 'human' because of their small(er) brain. Perhaps a strange thought, but I was really wondering: If we could place a human brain inside that of an animal: Would we be ...
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1answer
126 views

What is the neurophysiological mechanism behind double hearing?

A patient with sensorineural hearing loss can have the symptom of hearing "double" in the damaged ear. Not having a time-delayed echo, but hearing as if he (or other people) speak with "two voices" at ...
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3answers
1k views

What are current neuronal explanations and models of 'consciousness'?

I would like to understand more about consciousness from a neuroscientific perspective. I have a limited understanding of it in the philosophical/psychological sense through lectures. Although it is ...
10
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1answer
144 views

Are the center surround receptive fields learnt or inherited?

I know that neurons higher in visual pathways can learn their receptive fields after birth, but what about the connections between bipolar cells and Amacarine cells which form center/surround on/off ...
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1answer
47 views

Classical conditioning paradigm for hippocampal learning

I wanted to know what a suitable classical conditioning experiment would be to analyze learning and memory capabilities in rodent models with respect to hippocampal long-term potentiation (LTP). For ...
3
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1answer
71 views

What are the highest ranked neuroscience journals that use double-blind review process?

In terms of impact factor (for a lack of a better proxy), what are the highest ranked neuroscience journals that use double-blind review process? I would be submitting a paper that combines ...
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2answers
104 views

How many action potentials from presynaptic neurons would be required to make a postsynaptic neuron fire?

I am looking for a rough estimation of the number of action potentials from other neurons required to cause a neuron to fire? I read here that a potential of ~ -55mv must be reached before an action ...
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1answer
122 views

How similar are the brains of twins?

I am currently reading undergraduate essays on biological dysfunction and schizophrenia. The students put a lot of weight in the fact that studies of monozygotic twins show only a 50% rate of ...
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3answers
1k views

In what ways can neurons fire randomly?

When developing a model of a biologically-plausible neural network, it is important to know all the circumstances under which neurons can fire. But, I am limiting this question to random firing. In ...
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0answers
101 views

Have any drugs been shown to increase the neuroplasticity of adult brains?

I read recently in the book "meet your happy chemicals" that the hormones of puberty are neurochemicals that cause your neurons to connect and myelinate more easily. If this is true have any studies ...
8
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1answer
98 views

Comparative functional neuroanatomy: humans & octopodes

Cephalopod brains are toroidal (high surface area to volume ratios!), with the esophagus passing through the, uh, donut hole; octopodes are very intelligent, particularly spatially. Where can I find ...
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1answer
307 views

Can stress or training influence the perception of time?

I have had this experience that I fell with my bike on an icy street. During the fall time seemed to slow down and I had an apparent age-long time window to stretch my hand and safely catch my fall. ...
12
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1answer
234 views

What explains variability in the mean firing rate across biological neurons?

Biological neurons have a trade-off between high information transfer (high firing rate) and energy conservation (low firing rate). One would suspect that the maximization of this function has a ...
9
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1answer
72 views

Does an action potential abolish an excitatory postsynaptic potential?

From some sources, I've read that excitatory postsynaptic potentials (EPSPs) decay over time, which would imply that they aren't abolished by action potentials. However, other sources seem to indicate ...
8
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1answer
200 views

Why is it easier to fall asleep in the dark?

I'm curious if there is any neurological mechanism that explains why falling asleep is easier in the dark. I recognize that this isn't true universally -- a phobia of darkness might make it easier to ...
3
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1answer
93 views

What is the neurobiological difference between Jungian Judging and Perceiving individual?

Jungian or Myers Briggs type indicator reserves the last letter of a 4 letter archetype to stand for Judging or Perceiving. Part of being a Judging type is punctuality - being on time, keeping ...
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2answers
175 views

Which are the multisensory brain areas?

What would be an example of a multisensory brain area, where multiple senses (e.g. smell and taste) are combined to decode the corresponding stimuli from more than one sensory organ? I was thinking ...
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1answer
221 views

Can prolonged neural adaptation lead to HPPD?

The human brain adapts to a constant stimulus of our neural system. For instance, if we ride a train and look out of the window for a long time and the train stops, we have the feeling of slowly ...
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2answers
811 views

What is the “static” in human vision called?

Sort of like a cheap digital Camera, the human eye has certain feedback that's perceived but doesn't actually exist in the real world; a little layer of Static that's especially noticeable in pitch ...
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1answer
57 views

Is the weight of neural inputs in the human brain as central as it is for neurons in an artifical neural network?

As an example of an artificial neural net (ANN), a neural processing unit (NPU) is able to encode previous (learned) information by storing a weighted resistance for each input. Since ANN's are ...
4
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1answer
274 views

Why do some people stutter only when they are nervous?

Background: I don't stutter at least not always. For example, if I be reading out a article to myself, It is sure that I will not stutter even that I am reading it out loud. The times when I do ...
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41 views

Is movement/activity level related to serotonin availability or reuptake rates in the brain?

I'm aware of this research article that explores the relationship between motion and serotonin systems: 5-HT and motor control: a hypothesis. Based on the article above, it seems to me that a "very ...
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1answer
71 views

What is so “potential” about action potentials?

When an action potential is propagating through a neuron, it seems to me that the time for "potential of action" is over, and that we are now just in a state of "action". Why don't we just call action ...
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1answer
114 views

Do widespread brain toxins explain violence rates?

Saw this: http://www.motherjones.com/environment/2013/01/lead-crime-link-gasoline Lead emissions from tailpipes rose steadily from the early '40s through the early '70s, nearly quadrupling over ...
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1answer
399 views

What's the difference between executive functions and cognitive control?

I suspect that the difference between these terms may vary from researcher to researcher, since the wikipedia page treats them as synonymous. What's the difference between executive functioning and ...
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1answer
115 views

What are the neurobiological factors related to depression?

While it is agreed that neurotransmitters aren't the primary "cause" of depression, what other factors are a part of this mental illness that focus on the neurobiological aspects of it?
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1answer
304 views

How are qualia localized in consciousness?

I understand that evolution incorporated arbitrary qualia into the default network to inform consciousness (the largest cranial global processing information subnetwork) about properties and qualities ...
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1answer
88 views

Difference in frequencies of mistakes between use of left-right vs. up-down

I have no hard data, but from my personal experience in people specifying right or left directions (similarly east or west) and up or down (north or south, top or bottom), people frequently make ...
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1answer
55 views

How does Parkinson's disease result in tremors?

From what I understand, Parkinson's disease is caused by the death of dopamine producing cells in the substantia nigra, however I don't understand how that causses the symptoms of Parkinson's. I am ...
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0answers
131 views

What are the brain regions related to tinnitus shown in this figure?

I am interested in learning about the neural mechanisms behind tinnitus, and was wondering if someone could help me to name the parts of the brain on this image that show increased activity in ...
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3answers
1k views

What do the super-large brains of whales and elephants map to?

Elephants and whales have brains that are much larger than those of humans. It is presumed that much of their brain is used up for their larger bodies (after all, there is a allometric scaling between ...
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0answers
41 views

Psychological problem with glasses and hats on head? [closed]

I knew a kid who, when they was little, they would have attacks when a relative removed their glasses. She would sometimes do it on purpose in front of them and they would have emotional outbursts ...
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1answer
108 views

Visual acuity and offset stimuli

I'm currently setting up and experiment that utilises a visual search task that contains a circular array of target letters and a distractor that falls outside the circle. Obviously the further away ...
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86 views

What are the smallest neurons ever identified? [closed]

What are the smallest neurons ever measured? I'm happy with any superlatives, such as the thinnest axons or dendrites, smallest somata etc. Thank you :)
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2answers
339 views

How do SSRIs work?

I've found a reasonable explanation on Wikipedia... SSRIs are believed to increase the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, ...
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1answer
40 views

Determining the position of the calcium ion in the three dimensional space

Is it possible to determine the position of a single calcium ion or its population in the context of a three dimensional space with relatively good time frequency, say 1 Hz, taking into account ...
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0answers
41 views

How does de-myelination occur in multiple sclerosis? [closed]

From what I understand, only the oligodendrocytes are affected in multiple sclerosis, and they are attacked by T cells which cross the blood-brain barrier. This leads me to two questions: How is the ...
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2answers
156 views

Long term effect of using noise generators

Some people use noise generators as http://playnoise.com/ to reduce distraction by background noise. Is there any research on the long term effects of this? Does this affect the neuronal connections ...
3
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1answer
125 views

Is meaning-seeking behavior a biological optimization problem?

In short, I'm interested in cognitive, neuroscientific, biological and/or computational perspectives on what we vaguely refer to as meaning seeking. Of course, this is a large topic, but any ...
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2answers
203 views

Colorado Boulder study about brain morphometric measures of Cannabis users methodologically weak?

I'm relating to this study: http://www.jneurosci.org/content/35/4/1505.short The researchers found no differences in subcortical brain structures for daily Cannabis users vs. controls. However the ...
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2answers
281 views

Are there mental reflexes?

Similar to knee-jerk or withdrawal, are there any innate reflexes in cognition? Are they based on personality, or are there any that are universal?
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1answer
42 views

How does my spinal cord know to take reflexive action?

As in, how does my body know that a stove is not hot enough to warrant a reflex? Is it because there isn't a sudden electrical surge going through the nervous system?
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0answers
46 views

Why does the unilateral 6-OHDA lesion Parkinson's model cause ipsilateral rotations?

As far as I understand, the loss of dopaminergic neurons should hinder movement in the contralateral side of the body, resulting in contralateral rotations when the animal tries to move forward.
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2answers
78 views

Activity in a brain region and additional blood requirement: What is the causal relation?

May I know causal dependence of the blood flow in the brain? How it is determined by the brain that particular brain region requires additional blood?
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1answer
80 views

Why is the order of brainwaves not labelled “alphabetically”?

The brainwave - frequency breakdown is as follows: Delta wave – (0.1 – 3 Hz) Theta wave – (4 – 7 Hz) Alpha wave – (8 – 15 Hz) Mu wave – (7.5 – 12.5 Hz) SMR wave – (12.5 – 15.5 Hz) Beta wave – (16 – ...
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1answer
526 views

How many dendrite connections vs axon terminals does a multipolar cerebral neuron have?

I find countless places that say neurons have tens of thousands of "connections" or "synapses" and one axon. Do neurons have tens of thousands of dendrite connections, and a few axon terminals; or a ...
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0answers
61 views

How can we use EEG data to predict urge of smoking?

I am from Computer Sciences background. The problem which I want to target is to be able to successfully predict (to a degree) that a person is going to smoke in near future. I have a brainwave ...
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1answer
30 views

Benefits of using more complicated neuron models in NEF models

The NEF allows you to use almost any neuron model as long as it has an equation for it's activity and it's spikes in some way. Usually, a simple leaky-integrate-fire (LIF) neuron model is used, but ...