For questions about the biology of the nervous system, from a macroscopic to microscopic perspective.

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Can tinnitus be measured with EEG or MEG?

Can tinnitus be measured with EEG or MEG (magnetoencephalography)? Is it visible in a power spectrum? In an ERP/ERF?
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132 views

When a person starts to scratch, why does this often start others to scratch?

Often, when a person starts scratching and complains of being itchy, whether they suggest there might be a bug biting them (for example fleas, head lice, mites) another person with them will start to ...
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88 views

How can the aversion response be explained neurologically?

If Dopamine and Dopamine D2 receptor is involved in craving, wanting and clinging towards something or incentive salience Dopamine is closely associated with reward-seeking behaviors, such as ...
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76 views

Structural descriptions of neuronal networks are important for understanding brain dysfunctions; which dysfunctions, in particular?

In a recent paper, we find this quote: The brain contains vast numbers of interconnected neurons that constitute anatomical and functional networks. Structural descriptions of neuronal network ...
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136 views

How is light processed by the human brain when awake and in dreams?

I've recently seen this great video: How your brain tells you where you are. The video discusses how certain cells within the brain fire based on proximity to objects. There are great examples of ...
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46 views

What exactly is the neurobiological mechanism behind the functioning of the human muscle?

From what I have read, its been given that muscle functioning and coordination involves two processes: frequency summation and muscle recruitment. What I want to know is that, do these two processes ...
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43 views

How many thalamocortical relay cells synapse onto each spiny stellate cell in neocortex?

I am curious about how many different thalamocortical relay cells synapse onto each layer IV spiny stellate cell, on average? The answer is likely to be different per region and species, of course. I ...
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55 views

Trying to understand equations in Karl Friston article

I am trying to understand a neuroscience article by Karl Friston. In it he gives three equations that are, as I understand him, equivalent or inter-convertible and refer to both physical and Shannon ...
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136 views

Does data support Domhoff's neurocognitive theory of dreams?

Background: A friend described consistent feelings and themes during a dream. It is my understanding that the contents of our dreams are our subconscious/unconscious/preconscious processing stimuli ...
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108 views

How can I test whether Dorsal Raphe Nucleus(DRN) activity at night is related to variations in mood?

I'm reading this paper, which discusses Serotonin activity in the Dorsal Ralphe Nucleus(DRN), and even includes some mathematical models of how serotonin is released and reabsorbed. The paper states ...
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437 views

Computational Neuroscience software

What are the most common software tools you use in your day to day work in computational neuroscience? I am referring to neuroscience tools like GENESIS and NOT to generic tools like Excel.
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613 views

Where is the visual “image” that we “see” finally assembled?

David Hubel's online book, Eye, Brain and Vision describes in great detail our early visual system. The image that we are conscious of when we open our eyes goes through a complex path: The final ...
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926 views

How do we get used to smells?

How do we get used to smells? For example, you walk into a room with a certain stench, but it seems no matter how strong it may be, spending enough time in the room will allow you to stop smelling ...
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161 views

Why does a neuron choose to connect to another?

I have been reading about neuron creation, guidance cues and all sorts of highly complex mechanisms used to allow one neuron axon to extend or connect - but to what end? Why does one neuron end up ...
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195 views

Physiological differences between brains of Conservatives and Liberals

I work for a non-profit research organization and I have been assigned to do research on this topic. I have been doing my best to find studies on this topic but every website and article seems to ...
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3answers
138 views

Is there a complete cortico-cortical connectivity map based on a useful partitioning of the cortex?

I have something like Brodmann Areas in mind, but any complete list of cortex regions would do. I'm primarily interested in human brains here. Ultimately I'd like enough information to be able to ...
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160 views

Colorado Boulder study about brain morphometric measures of Cannabis users methodologically weak?

I'm relating to this study: http://www.jneurosci.org/content/35/4/1505.short The researchers found no differences in subcortical brain structures for daily Cannabis users vs. controls. However the ...
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44 views

Why is the order of brainwaves not labelled “alphabetically”?

The brainwave - frequency breakdown is as follows: Delta wave – (0.1 – 3 Hz) Theta wave – (4 – 7 Hz) Alpha wave – (8 – 15 Hz) Mu wave – (7.5 – 12.5 Hz) SMR wave – (12.5 – 15.5 Hz) Beta wave – (16 – ...
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198 views

What are the neurobiological triggers for sleepwalking?

This phenomena has always fascinated me, ever since my parents told me (and filmed me) doing exactly that - sleepwalking. I have read the pamphlet "Sleepwalking" from the Sleep Health Foundation, ...
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64 views

Activity in a brain region and additional blood requirement: What is the causal relation?

May I know causal dependence of the blood flow in the brain? How it is determined by the brain that particular brain region requires additional blood?
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84 views

Difference between brain disease and brain disorder

Is there any difference between the terms brain disease and brain disorder? They are often used in combination without ...
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79 views

What is the lifetime of the synapse in the mature brain?

I know there is synaptic plasticity in the mature brain. There is a great number of plasticity mechanisms like LTD and LTP, acting on different time scales. Apart from the synaptic weight change, ...
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146 views

Is it possible to objectively measure the amount of pleasure a person is experiencing?

I'd like to know if it's possible to quantify somebody's "fun meter". Maybe by measuring the amount of endorphin produced. Because every person is unique, I don't expect that amount to make another ...
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110 views

How does chronic stress improve memory processes?

There seems to be more information on the detrimental effects of stress on memory. There is evidence to the contrary. Stress effects on memory: an update and integration. Schwabe L, et al doi: ...
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287 views

What brain skill does Nonogram (Picross) games develop?

I've been playing Nonogram Picross a lot lately. I really like it and you can always find a harder challenge but I would hate to waste my time for nothing. What brain skill does Nonogram (Picross) ...
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95 views

Does the Hodgkin-Huxley Model take into account the action of the ion pumps (e.g., Na-K-ATPase)?

After the firing of a neuron, the sodium and potassium concentration differences vanish. It requires some time for cell to actively transport the ions in and out to re-establish the balance. Does ...
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Visual acuity and offset stimuli

I'm currently setting up and experiment that utilises a visual search task that contains a circular array of target letters and a distractor that falls outside the circle. Obviously the further away ...
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52 views

If one is flexing a muscle, for any given motoneuron involved, how many action potentials occur per second to keep the muscle flexed?

Also, will the axon terminals in a given motoneuron ever run out of neurotransmitters to release if they are constantly undergoing action potentials (say in the situation outlined above where a muscle ...
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603 views

How can motivation be increased by improving brain chemistry with nutrition and activities?

I'm reading some material about motivation and brain chemistry. One of the interesting articles is "7 Ways to Increase Motivation by Improving your Brain Chemistry". I'm interested in a more ...
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216 views

Does each sensory neuron type have a characteristic spike sequence pattern?

Background It is known that all sensory information is input to the brain as neural spike sequences. Now, to distinguish between the spike sequences generated by retinal red/blue/green cone cells ...
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33 views

How many dendrite connections vs axon terminals does a multipolar cerebral neuron have?

I find countless places that say neurons have tens of thousands of "connections" or "synapses" and one axon. Do neurons have tens of thousands of dendrite connections, and a few axon terminals; or a ...
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1answer
114 views

MRI images upside-down in FSLVIEW

I'm visualizing structural data in FSLVIEW, but the sagittal and coronal planes are both upside-down / not in the conventional orientation, i.e. rotated by 90º and 180º. I understand that this ...
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1answer
74 views

What does a cortical column do?

The Blue Brain project led by Henry Markram focused on simulating cortical columns under the idea they form basic processing units of the brain/cognitive function. What does a cortical column do? I ...
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183 views

How do SSRIs work?

I've found a reasonable explanation on Wikipedia... SSRIs are believed to increase the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, ...
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127 views

What neurobiological changes are associated with the end of the critical period in children?

Developing children are in a critical period during which they are much better at learning certain tasks like speaking a language. After the critical period ends, children have a qualitatively more ...
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108 views

What is the neurobiological basis of the “inner voice” used for thought or reading?

I've recently experienced a number of hypnogogic near sleep states characterized by change in thinking (stage 1-2 sleep). I noticed that if I let go and get absorbed in the state, I can follow it. I ...
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52 views

To what degree does environment govern the severity of symptoms in schizophrenia?

From what I understand about the physiology of schizophrenia it is thought to be caused by chemical imbalances resulting from genetic factors, fueled by environmental factors. I've garnered that ...
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115 views

What biological processes occur when you love someone romantically? [closed]

How can romantic love be described by scientists?
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64 views

When did neurotransmitters derived from monoamines first appear in evolutionary history?

When did neurotransmitters derived from monoamines first appear in evolutionary history? What are main the points in evolution for monoamines based on the neurotransmitter system ? Edition I'm ...
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205 views

How are qualia localized in consciousness?

I understand that evolution incorporated arbitrary qualia into the default network to inform consciousness (the largest cranial global processing information subnetwork) about properties and qualities ...
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174 views

Plot a schematic outline of the brain

I know that I can read, write and analyse different type of brain scanning data using various Medical Imaging Tools available for R. But I am looking for something very simple - a possibility to just ...
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326 views

Is human Central Nervous System arousal related to choice of activity?

I'm interested in learning more about the central nervous system (CNS) arousal and the choice of what people do and how they feel about it. Lets define CNS arousal in the context of this question as ...
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265 views

Neural Microfilaments for Computation?

I just watched an interesting TED talk (http://www.youtube.com/watch?v=1d5RetvkkuQ) where a Stuart Hameroff proposes that a neuron's microtubules are responsible for computations, and that they are ...
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153 views

What are the effects of implanting electrodes into the brains of monkeys?

If one implants electrodes into a monkey's brain in order to allow the monkey to control a mechanical arm, then is the monkeys able to move both it's natural and it's mechanical arms at once? What ...
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3answers
190 views

How are personality traits “encoded” in the brain?

How are personality traits – such as optimism, sensation seeking or need for cognition – "encoded" in the brain? Do people with different levels of, say, extraversion have different neuronal ...
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2answers
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Are the lobes of the brain anatomically distinct, or is the distinction between them not as well-defined?

If I had a brain in front of me, would I be able to find some kind of crevasse or something separately each lobe from the next? I guess what I'm asking is, are lobes more arbitrarily-defined regions ...
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115 views

Neurosurgically grown neural link between two brains?

I guess it's possible to surgically restore neural connection after a trauma (e.g. a severed hand can be reattached if done quickly). And, from history of evolution of hominids, it seems that just by ...
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99 views

Does a person experience release of dopamine while doing something she/he enjoys?

I am wondering if a person would experience an increase in the level of dopamine while doing something she/he enjoys such as playing guitar or reading a book. And what are some other neurotransmitter ...
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494 views

How does posture affect cerebral blood flow?

This is a follow-up question to an answer on Quora: In the upright posture, venous outflow is considerably less pulsatile (57%) and occurs predominantly through the vertebral plexus, while in ...
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40 views

Are there mental reflexes?

Similar to knee-jerk or withdrawal, are there any innate reflexes in cognition? Are they based on personality, or are there any that are universal?