For questions about the biology of the nervous system, from a macroscopic to microscopic perspective.

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6
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2answers
217 views

What is the neurobiological basis of the “inner voice” used for thought or reading?

I've recently experienced a number of hypnogogic near sleep states characterized by change in thinking (stage 1-2 sleep). I noticed that if I let go and get absorbed in the state, I can follow it. I ...
7
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1answer
255 views

Does adult neurogenesis occur only in the olfactory bulb and the hippocampus?

The scholarpedia article on this subject says: Adult neurogenesis is the process of generating new neurons which integrate into existing circuits after fetal and early postnatal development ...
8
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2answers
137 views

What is the result of an excess of dopamine?

I'm pretty familiar with the results of having not enough dopamine, though the reasons are not so clear to me. To get a better insight on the topic I'd like to know something about having too much ...
0
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0answers
30 views

Results from machine learning converging with results from neuroscience [closed]

I'm currently picking up deep learning, which is a trending method in the field of machine learning that have recently gained fame for breaking various records (for example in image recognition). It ...
9
votes
1answer
140 views

Why does strobe lighting trigger seizures in photosensitive epilepsy?

Photosensitive epilepsy (PSE) is a form of epilepsy in which seizures are triggered by visual stimuli that form patterns in time or space, such as flashing lights, bold, regular patterns, or ...
6
votes
1answer
89 views

How does it come about that specific areas of the brain are associated with specific functions?

During the development of the human brain, specific areas come to perform specific functions. How (and when) does this differentiation come about? Presumably, some areas of the brain naturally take ...
5
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1answer
49 views

Does synesthesia lack symmetry?

Some synesthetes report seeing bright flashes when hearing a loud noise. However, in the same person, bright flashes of light are not reported as being loud. I've read of other examples like this; ...
8
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2answers
164 views

Is there a difference between hearing and decoding the sound?

I presume that deafness is the inability of hearing any sounds. And I presume that it may also be possible to be less able to decode sounds. In other words, an inability to translate or understand the ...
1
vote
1answer
102 views

Can Transcranial Magnetic Stimulation (TMS), or a magnets cap make you smarter?

According to wikipedia, TMS is a bunch of magnetic fields directed to the brain which stimulates and activates neurons. If I wear a cap full of magnets, will it stimulate my neurons? If yes, will a ...
2
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0answers
34 views

Neurobiology of addiction recovery [closed]

While addiction is one of the most studied topics in neurobiology, I don't see very much info on recovery. The information I have found is confusing. This one says striatal DAT bindings return to ...
4
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0answers
32 views

How are psychological bio-markers discovered?

Recently, this paper claiming to be able to distinguish bipolar disorder from major depressive disorder via a urine sample has come to my attention. Despite reading the paper, I'm unable to ...
1
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1answer
46 views

Parasite that takes over cognitive functions [closed]

I am testing an idea for a book. The backbone of the story is that there exists a parasite that can enter the brain of a creature and take over its cognitive functions. I imagine that it could wire ...
6
votes
1answer
84 views

Are the human cerebral hemispheres only connected via the corpus callosum?

Are the human cerebral hemispheres only connected via the corpus callosum? Or is there any other structure for interaction between the left and right hemispheres?
3
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2answers
80 views

Are action potentials necessary for experience?

We know that, for example, during brain surgery, electrical stimulation in certain parts of the cortex is sufficient for experience, and result in reportable experiences in human subjects. We also ...
4
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2answers
1k views

What is the role of Chloride (Cl- ions) in membrane potential?

This Membrane Potential article mentions only that Cl- ion is used to model inhibitory GABA synapses. Does it have another role besides hyper-polarizing the cell due to inhibitory neurotransmitter ...
6
votes
2answers
174 views

How do neurons decide how to alter their output signals?

In computer science, neural networks are trained using backpropagation and other methods. Backpropagation heavily relies on mathematical formulas to describe how the weights should be changed ...
1
vote
1answer
54 views

Unified Theory of the Human Brain [closed]

I'm a junior researcher(Life Sciences undergraduate) starting out in computational genetics of neuroscience, and I want to create a Unified Theory/Computational Model of the human brain and all its ...
1
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0answers
107 views

Lifelong avoidance coping style [closed]

Suppose someone has been using avoidance coping style for most of his or her life. The avoidance tendency is present in a broad range of situations, relatively constant through his or her life, not ...
2
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2answers
351 views

Explanatory gaps in the formation and propagation of action potentials

To my understanding, the steps of an action potential are as follows: The neuron is at rest--there is a negative charge (K ions) inside the cell, and a positive charge (Na ions) outside the cell. ...
3
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1answer
100 views

How can pain sensations appear to originate within the person's skull?

I've read that humans have some sort of a kinesthetic model of their body and muscles. This internal representation of the body is used to control and coordinate locomotion. I don't remember if ...
5
votes
1answer
140 views

Is there a biological limit for “amount” of happiness?

I have heard about neurotransmitters like dopamin and serotonin that are supposed to play a role in our feeling of happiness. I don't know how these chemicals works in our brain, but I am thinking ...
3
votes
1answer
328 views

Does reading a book out loud make you better in social situations?

Suppose a person reads a book out loud for 1 hour straight. Would this "exercise" the parts of the brain involved in speech? Would this make the person a better communicator in social situations?
4
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0answers
53 views

What personality traits correlate with estrogen?

I'm looking for psychological traits that are proved to correlate with estrogen levels. Anything of specific behavior, attitudes, life styles, emotions, preferences, you name it. (I'm looking for ...
3
votes
2answers
71 views

Result of local stimulation in brain

What happens when we stimulate a brain in local regions? Some possibilities: We may trigger an action without the subject's awareness of the action; We can trigger an action in a subject, but we ...
4
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0answers
39 views

How does oxygen deprivation affect neural activity?

It is increasingly common for someone to regain a heartbeat after a cardiac arrest. During the time that the person is without a heartbeat, and so without circulation, the brain is deprived of oxygen. ...
8
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0answers
48 views

What exactly is an astroglial calcium wave?

There are quite a few conflicting reports as to what stimulates them, how they propagate, whether they communicate intercellularly, and what they look like. The only consistent information I can ...
2
votes
4answers
196 views

If a human brain would be placed inside that of an animal: Could it talk?

Assumption: Animals can't talk 'human' because of their small(er) brain. Perhaps a strange thought, but I was really wondering: If we could place a human brain inside that of an animal: Would we be ...
6
votes
1answer
112 views

What is the neurophysiological mechanism behind double hearing?

A patient with sensorineural hearing loss can have the symptom of hearing "double" in the damaged ear. Not having a time-delayed echo, but hearing as if he (or other people) speak with "two voices" at ...
29
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3answers
1k views

What are current neuronal explanations and models of 'consciousness'?

I would like to understand more about consciousness from a neuroscientific perspective. I have a limited understanding of it in the philosophical/psychological sense through lectures. Although it is ...
10
votes
1answer
142 views

Are the center surround receptive fields learnt or inherited?

I know that neurons higher in visual pathways can learn their receptive fields after birth, but what about the connections between bipolar cells and Amacarine cells which form center/surround on/off ...
7
votes
1answer
47 views

Classical conditioning paradigm for hippocampal learning

I wanted to know what a suitable classical conditioning experiment would be to analyze learning and memory capabilities in rodent models with respect to hippocampal long-term potentiation (LTP). For ...
3
votes
1answer
67 views

What are the highest ranked neuroscience journals that use double-blind review process?

In terms of impact factor (for a lack of a better proxy), what are the highest ranked neuroscience journals that use double-blind review process? I would be submitting a paper that combines ...
2
votes
2answers
90 views

How many action potentials from presynaptic neurons would be required to make a postsynaptic neuron fire?

I am looking for a rough estimation of the number of action potentials from other neurons required to cause a neuron to fire? I read here that a potential of ~ -55mv must be reached before an action ...
8
votes
1answer
121 views

How similar are the brains of twins?

I am currently reading undergraduate essays on biological dysfunction and schizophrenia. The students put a lot of weight in the fact that studies of monozygotic twins show only a 50% rate of ...
12
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3answers
969 views

In what ways can neurons fire randomly?

When developing a model of a biologically-plausible neural network, it is important to know all the circumstances under which neurons can fire. But, I am limiting this question to random firing. In ...
4
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0answers
94 views

Have any drugs been shown to increase the neuroplasticity of adult brains?

I read recently in the book "meet your happy chemicals" that the hormones of puberty are neurochemicals that cause your neurons to connect and myelinate more easily. If this is true have any studies ...
8
votes
1answer
98 views

Comparative functional neuroanatomy: humans & octopodes

Cephalopod brains are toroidal (high surface area to volume ratios!), with the esophagus passing through the, uh, donut hole; octopodes are very intelligent, particularly spatially. Where can I find ...
9
votes
1answer
301 views

Can stress or training influence the perception of time?

I have had this experience that I fell with my bike on an icy street. During the fall time seemed to slow down and I had an apparent age-long time window to stretch my hand and safely catch my fall. ...
12
votes
1answer
234 views

What explains variability in the mean firing rate across biological neurons?

Biological neurons have a trade-off between high information transfer (high firing rate) and energy conservation (low firing rate). One would suspect that the maximization of this function has a ...
9
votes
1answer
72 views

Does an action potential abolish an excitatory postsynaptic potential?

From some sources, I've read that excitatory postsynaptic potentials (EPSPs) decay over time, which would imply that they aren't abolished by action potentials. However, other sources seem to indicate ...
8
votes
1answer
179 views

Why is it easier to fall asleep in the dark?

I'm curious if there is any neurological mechanism that explains why falling asleep is easier in the dark. I recognize that this isn't true universally -- a phobia of darkness might make it easier to ...
3
votes
1answer
85 views

What is the neurobiological difference between Jungian Judging and Perceiving individual?

Jungian or Myers Briggs type indicator reserves the last letter of a 4 letter archetype to stand for Judging or Perceiving. Part of being a Judging type is punctuality - being on time, keeping ...
11
votes
2answers
173 views

Which are the multisensory brain areas?

What would be an example of a multisensory brain area, where multiple senses (e.g. smell and taste) are combined to decode the corresponding stimuli from more than one sensory organ? I was thinking ...
7
votes
1answer
218 views

Can prolonged neural adaptation lead to HPPD?

The human brain adapts to a constant stimulus of our neural system. For instance, if we ride a train and look out of the window for a long time and the train stops, we have the feeling of slowly ...
11
votes
2answers
793 views

What is the “static” in human vision called?

Sort of like a cheap digital Camera, the human eye has certain feedback that's perceived but doesn't actually exist in the real world; a little layer of Static that's especially noticeable in pitch ...
3
votes
1answer
55 views

Is the weight of neural inputs in the human brain as central as it is for neurons in an artifical neural network?

As an example of an artificial neural net (ANN), a neural processing unit (NPU) is able to encode previous (learned) information by storing a weighted resistance for each input. Since ANN's are ...
9
votes
2answers
103 views

How is tone volume encoded?

I am wondering whether increasing the volume would result in (a) a neuron that was already firing to now increase its spike rate, (b) a different group of neurons to add their activity to the ...
4
votes
1answer
235 views

Why do some people stutter only when they are nervous?

Background: I don't stutter at least not always. For example, if I be reading out a article to myself, It is sure that I will not stutter even that I am reading it out loud. The times when I do ...
5
votes
0answers
40 views

Is movement/activity level related to serotonin availability or reuptake rates in the brain?

I'm aware of this research article that explores the relationship between motion and serotonin systems: 5-HT and motor control: a hypothesis. Based on the article above, it seems to me that a "very ...
2
votes
1answer
70 views

What is so “potential” about action potentials?

When an action potential is propagating through a neuron, it seems to me that the time for "potential of action" is over, and that we are now just in a state of "action". Why don't we just call action ...