For questions about the biology of the nervous system, from a macroscopic to microscopic perspective.

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Is serotonin conclusively linked to depression?

Some highlights from this article: http://www.thedailybeast.com/newsweek/2010/01/28/the-depressing-news-about-antidepressants.html ever since a seminal study in 1998, whose findings were ...
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2answers
267 views

Are different types of long term memories stored in different parts of the brain?

I recently had some questions concerning the capacity of the brain's memory: Are different types of long term-memories like know-how, your-life, etc. remembered in different parts of the brain? If ...
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118 views

Long term effect of using noise generators

Some people use noise generators as http://playnoise.com/ to reduce distraction by background noise. Is there any research on the long term effects of this? Does this affect the neuronal connections ...
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1answer
190 views

Fusiform Face Area (FFA) for within class recognition?

Is there any evidence (papers, studies, etc) that the Fusiform Face Area is used for any other type of recognition besides facial recognition? I remember hearing or reading a long time ago that ...
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1answer
236 views

Is performance reducible to brain activity in an unambiguous way?

As a preface, let me assume that the entirety of mental states and their corresponding behaviors in a person are entirely reducible to the physical activity of neurons sending a variety of chemicals ...
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1answer
90 views

Comparative functional neuroanatomy: humans & octopodes

Cephalopod brains are toroidal (high surface area to volume ratios!), with the esophagus passing through the, uh, donut hole; octopodes are very intelligent, particularly spatially. Where can I find ...
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1answer
266 views

Can stress be detected by an fMRI?

How does stress damage the brain (if at all)? Is it akin to taking drugs, heavy drinking, or a minor stroke? Would an fMRI of a stressed person present evidence of stress?
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1answer
115 views

What is the role of traveling waves in circuit formation during cortical development?

Propagating waves of activity have been characterized in various regions of the brain such as the visual cortex (Nauhaus et al., 2012). Recently they have been reported for the first time to occur ...
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1answer
113 views

Is there a report of a successfully EEG-Based Brain-Computer Interface (BCI) using image training?

Currently I am involved in constructing an EEG-Based BCI. The goal of the BCI is to control which light in a series of lightbulbs lights up. The plan is to use different images (i.e. a flower versus ...
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90 views

Have there been any mechanisms proposed for normalization in probabilistic population codes?

I heard a talk yesterday by Dora Angelaki about multi-sensory integration. Part of the talk was about bayesian inference with multiple noisy sources of information. I know that there has been a lot ...
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51 views

How actively does your brain physically prune connections?

Is pruning defined as neural apoptosis or are connections (neural synapses) simply separated? At what rate, if known, does this occur in individuals (ages 18+)?
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1k views

What is the difference between pre-synaptic versus post-synaptic?

I am unclear as to the exact meaning of the terms pre-synaptic and post-synaptic. Specifically, do they refer to the same neuron, either transmitting or receiving, before and after the chemical ...
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340 views

Is an autistic person's brain different from a non-autistic one?

Are there any differences between the autistic person's brain and the non-autistic one? To be more specific, are there any differences in brain structure or brain activity, that can be used to ...
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341 views

Non coitus sexual activity and the brain

Most animals will only engage in sexual activity that can result in reproduction. There are some exceptions; Bonobos, for instance, engage in a lot of sexual activity that does not involve coitus. ...
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1answer
144 views

Hebbian Learning Rule, Local or Global?

I just learned about the Hebbian Learning Rule. It essentially says "Neurons that fire together, wire together". I'm wondering if the learning rule is affected by the spatial distance of the two ...
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3answers
149 views

Can neural spiking in an organism temporarily cease?

I'm interested in modeling human brain spiking activity. Are there cases in which neural spiking completely ceases in an organism and yet later resumes? I've considered: hypothermic drowning, but ...
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1answer
240 views

What is a neurobiological explanation of borderline personality disorder?

In other words, how do the brains of those with BPD differ from those who don't have BPD? The Wikipedia article doesn't even contain any possible explanations whatsoever.
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174 views

Abstract idealized mental visualization improves motor task performance

I practice martial arts (Aikido), which involves a lot of rotation. When practicing, I find that holding an abstract image in my head, instead of thinking about the actual technique, improves my ...
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1answer
4k views

Which neurotransmitters can be measured in a living human brain?

I'm interested in learning more about the modern techniques that are used for scientific studies of neurotransmitters in the living human brain. As far as I know, there are 4 neuromodulator systems ...
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1answer
257 views

Can stress or training influence the perception of time?

I have had this experience that I fell with my bike on an icy street. During the fall time seemed to slow down and I had an apparent age-long time window to stretch my hand and safely catch my fall. ...
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1answer
605 views

What is the relationship between sociology and cognitive sciences?

I want to know what is the relationship between sociology and cognitive sciences. Let me start by short consideration of both: Sociology - well established discipline or a field of research ...
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255 views

How do SSRIs work?

I've found a reasonable explanation on Wikipedia... SSRIs are believed to increase the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, ...
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1answer
76 views

How does one study the effect of a dietary supplement on cognition?

I've really enjoyed this talk by Molly Crockett: Beware neuro-bunk. The speaker outlines the limitations of modern neuroscience when accessing the effectiveness of dietary supplements intended to ...
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1answer
239 views

What computerized EEG analysis algorithms are there?

I got a commercial-grade EEG headband and am trying to look at the data it outputs. The headband quantifies raw EEG signal from a single forehead dry sensor into a range of EEG bands (alpha, beta, ...
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1answer
91 views

What can be inferred about the strength of the synapse from an electron microscope image?

In the following EM image (1um scale), there are several synapses: Image or HD Version What information about the synaptic strengths can be extracted from this image? Does vesicle count contain ...
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1answer
121 views

Why is it easier to fall asleep in the dark?

I'm curious if there is any neurological mechanism that explains why falling asleep is easier in the dark. I recognize that this isn't true universally -- a phobia of darkness might make it easier to ...
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1answer
117 views

Why does strobe lighting trigger seizures in photosensitive epilepsy?

Photosensitive epilepsy (PSE) is a form of epilepsy in which seizures are triggered by visual stimuli that form patterns in time or space, such as flashing lights, bold, regular patterns, or ...
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1answer
112 views

Dopamine deficiency more frequent in the addiction prone?

I found this clip about dopamine deficiency. ...[P]eople with low dopamine activity may be more prone to addiction. Is the reverse also true? Does susceptibility to addiction (genetic, etc.) ...
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103 views

Can processing effort for sub-tasks in neural networks be measured?

I often heard statements like: 80% of your brain processing is computing the effect of gravity or, similarily: You only use 20% of your brain power My question isn't about the truth of ...
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1answer
59 views

Does an action potential abolish an excitatory postsynaptic potential?

From some sources, I've read that excitatory postsynaptic potentials (EPSPs) decay over time, which would imply that they aren't abolished by action potentials. However, other sources seem to indicate ...
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1answer
48 views

Number of presynaptic inputs per cell in primary visual cortex

I have been digging in the literature lately, but I haven't found a nice answer with clear cut numbers (avg +- std) to this question: How many presynaptic inputs receives a pyramidal cell in primary ...
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186 views

Does data support Domhoff's neurocognitive theory of dreams?

Background: A friend described consistent feelings and themes during a dream. It is my understanding that the contents of our dreams are our subconscious/unconscious/preconscious processing stimuli ...
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288 views

Do expert computer gamers have unusual physiological or mental characteristics? [duplicate]

Possible Duplicate: Any work being done on Perception, Action, and/or Cognition in Video games? Are there any research studies that show this? See a thread on Quora for some initial ...
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2answers
14k views

Why are some people unable to easily memorize the lyrics to a song?

Although I have listened some songs hundred of times I can't sing the lyrics to any of these songs from beginning to end without pauses. However I am able to whistle the whole song without difficulty. ...
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353 views

How would synapses behave if resting potential was zero?

Assuming that the resting potential is zero and the other mechanisms were exactly the same, how would it affect the generation of spikes in terms of excitatory and inhibitory postsynaptic ...
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99 views

Is there a difference between hearing and decoding the sound?

I presume that deafness is the inability of hearing any sounds. And I presume that it's also possible to be less able to decode (and translate to a meaningful message) what others speak [happens a lot ...
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2answers
167 views

What does daytime actigraphy reveal about an active and awake brain?

I have interest in the study of human motion ( Actigraphy), and have built a couple of smartphone apps using its principles. The apps look at gross motor activity of an individual. Up until now, most ...
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2answers
266 views

Why is MATLAB so common in Neuroscience?

It is common knowledge that neuroscience -- particularly experimental neuroscience -- uses MATLAB more than any other programming language. I have always just taken this as a given, and pointed to ...
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1answer
119 views

What are the neurological differences between those who have a high tolerance to pain and those who do not?

I am curious to learn what are the neurological differences between those that have a high tolerance to pain than to those that do not. Specifically, by high tolerance to pain, I am referring to ...
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70 views

Do the colour blind have a distinct visual cortex structure?

Studying the structure of the visual cortex, it seems there are many neural structures specifically dedicated to detecting and interpreting colour. For example, parvocellular cells are particularly ...
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1answer
84 views

How is epigenetic memory expressed in neurons?

Epigenetic memory is seen as the most evolutionarily plausible way of learning from experiences and gaining instinctual knowledge, as established by the answer to one of my previous questions. ...
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1answer
176 views

Can prolonged neural adaptation lead to HPPD?

The human brain adapts to a constant stimulus of our neural system. For instance, if we ride a train and look out of the window for a long time and the train stops, we have the feeling of slowly ...
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1answer
243 views

Measuring changes in hemispheric dominance over time

I've recently started using my trackball left-handed after being right-handed my whole life. The motivation is partly to balance out wrist strain, and partly to see how much my brain rejects the idea. ...
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1answer
72 views

Visual acuity and offset stimuli

I'm currently setting up and experiment that utilises a visual search task that contains a circular array of target letters and a distractor that falls outside the circle. Obviously the further away ...
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1answer
139 views

Classic cognitive neuroscience studies that highlight conclusions that could not be drawn from behavioral experiments

Background: I studied psychology prior to going into cognitive neuroscience for my PhD. While I know my own area in depth, I lack the kind of broad overview that people who have done their Masters in ...
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1answer
135 views

Introductory resources on developmental psychology/neuroscience

I'd like to be able to answer questions such as: What neuro/psychological functions underly competences such as empathy (or others - see background below)? What neurotransmitters are of particular ...
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1answer
414 views

Neurotransmitters appearance in the evolutionary process

Recently I disagreed with the assumption, that lots of neurotransmitters came within recent 10,000 years of Homo Sapiens evolution. Judging from the available information sources, there is possibility ...
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2answers
138 views

Grid cells : Between what is the correlation of autocorrelogram measured?

In their seminal paper Hafting, Torkel, et al. "Microstructure of a spatial map in the entorhinal cortex." Nature 436.7052 (2005): 801-806.‏ the Mosers have discovered the grid cells. To show the ...
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1answer
256 views

Transsexuality in animals other than humans?

In some research papers, transsexuality is correlated with measurable differences in brain structure. For example: Zhou et al. (1995) inspected the central subdivision of the bed nucleus of the ...
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1answer
86 views

In a central pattern generator based on reciprocal inhibition, how does one “side” get picked over the other to start out?

Consider two neurons, A and B, which reciprocally inhibit each other. If both of the neurons receive input at the same time, it seems to me that no oscillation will occur between the two. Such would ...