For questions about the biology of the nervous system, from a macroscopic to microscopic perspective.

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1answer
36 views

Determining the position of the calcium ion in the three dimensional space

Is it possible to determine the position of a single calcium ion or its population in the context of a three dimensional space with relatively good time frequency, say 1 Hz, taking into account ...
5
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0answers
29 views

How does de-myelination occur in multiple sclerosis? [closed]

From what I understand, only the oligodendrocytes are affected in multiple sclerosis, and they are attacked by T cells which cross the blood-brain barrier. This leads me to two questions: How is the ...
8
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2answers
118 views

Long term effect of using noise generators

Some people use noise generators as http://playnoise.com/ to reduce distraction by background noise. Is there any research on the long term effects of this? Does this affect the neuronal connections ...
3
votes
1answer
97 views

Is meaning-seeking behavior a biological optimization problem?

In short, I'm interested in cognitive, neuroscientific, biological and/or computational perspectives on what we vaguely refer to as meaning seeking. Of course, this is a large topic, but any ...
4
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2answers
183 views

Colorado Boulder study about brain morphometric measures of Cannabis users methodologically weak?

I'm relating to this study: http://www.jneurosci.org/content/35/4/1505.short The researchers found no differences in subcortical brain structures for daily Cannabis users vs. controls. However the ...
3
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2answers
66 views

Are there mental reflexes?

Similar to knee-jerk or withdrawal, are there any innate reflexes in cognition? Are they based on personality, or are there any that are universal?
2
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1answer
42 views

How does my spinal cord know to take reflexive action?

As in, how does my body know that a stove is not hot enough to warrant a reflex? Is it because there isn't a sudden electrical surge going through the nervous system?
4
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0answers
37 views

Why does the unilateral 6-OHDA lesion Parkinson's model cause ipsilateral rotations?

As far as I understand, the loss of dopaminergic neurons should hinder movement in the contralateral side of the body, resulting in contralateral rotations when the animal tries to move forward.
4
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2answers
72 views

Activity in a brain region and additional blood requirement: What is the causal relation?

May I know causal dependence of the blood flow in the brain? How it is determined by the brain that particular brain region requires additional blood?
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0answers
14 views

Smallest neurons [duplicate]

What are the smallest measured neurons ever measured in the animal kingdom? I did some research but couldn't find a definite answer. In us, it's the cerebellar granule cell as far as I know, but I'm ...
4
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1answer
49 views

Why is the order of brainwaves not labelled “alphabetically”?

The brainwave - frequency breakdown is as follows: Delta wave – (0.1 – 3 Hz) Theta wave – (4 – 7 Hz) Alpha wave – (8 – 15 Hz) Mu wave – (7.5 – 12.5 Hz) SMR wave – (12.5 – 15.5 Hz) Beta wave – (16 – ...
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0answers
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Do studies exist that can map specimens of neocortex to the functions they perform(ed) in vivo?

Much brain research has proposed that the brain (the neocortex, esp.) is set up in areas - an area for faces, an area for language, etc.. The experiments typically go 1) damage an area 2) observe ...
5
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1answer
64 views

How many dendrite connections vs axon terminals does a multipolar cerebral neuron have?

I find countless places that say neurons have tens of thousands of "connections" or "synapses" and one axon. Do neurons have tens of thousands of dendrite connections, and a few axon terminals; or a ...
2
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0answers
47 views

How can we use EEG data to predict urge of smoking?

I am from Computer Sciences background. The problem which I want to target is to be able to successfully predict (to a degree) that a person is going to smoke in near future. I have a brainwave ...
0
votes
1answer
15 views

Benefits of using more complicated neuron models in NEF models

The NEF allows you to use almost any neuron model as long as it has an equation for it's activity and it's spikes in some way. Usually, a simple leaky-integrate-fire (LIF) neuron model is used, but ...
3
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1answer
53 views

Can fMRI and EEG signals be generated from NEF models?

The basic function of the NEF is to map the outside world onto neurons, using the firing rates of the neurons. It also supports various neuron models. Have these firing rates been used to create EEG ...
3
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1answer
122 views

What is the difference between a biological and behaviorist perspective in psychology?

I was recently reading through a textbook and was unable to clearly identify the differences between the two due to a vague definition of both. Can someone provide an in-depth explanation of the two ...
2
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0answers
29 views

How can we analyse user behavior to predict urge of smoking?

The problem which I want to target is to be able to successfully predict (to a degree) that a person is going to smoke in near future. I want to look at the relationship between chemical reactions ...
3
votes
3answers
91 views

Can repetitive sports-related head injuries make a person senile many years later?

Would repetitive football injuries to the cranium show up decades later, causing symptoms resembling mild retardation, OCD, etc.? What is the best way to determine this in terms of imaging, testing, ...
0
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1answer
48 views

Regarding the mind and what it can affect

About the question 'Can the mind mind affect the brain?': Some responses are 'no' because the mind is a physical 'thing' or structure (if I read it correctly). Yet if the Mind is only a physical ...
21
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1answer
1k views

Have the abilities of John Lorber's patients with limited cortical mass been further evaluated in adulthood?

Short of minor lesions or infarcts, most high-functioning adults have an intact cerebral cortex. Yet, a surprising result published anecdotally in Science in 1980 caused a lot of scientists to take ...
3
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1answer
97 views

What are presynaptic puncta?

What are presynaptic puncta? And what makes them different from presynaptic terminals?
7
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2answers
987 views

What is the difference between pre-synaptic versus post-synaptic?

I am unclear as to the exact meaning of the terms pre-synaptic and post-synaptic. Specifically, do they refer to the same neuron, either transmitting or receiving, before and after the chemical ...
3
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0answers
35 views

Are there parts of the brain which don't change over a lifetime?

We know that during our lifetime the brain develops new neural connections and also there is pruning of neural connections. These phenomena together are called neuroplasticity. Is there any research ...
6
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2answers
138 views

Grid cells : Between what is the correlation of autocorrelogram measured?

In their seminal paper Hafting, Torkel, et al. "Microstructure of a spatial map in the entorhinal cortex." Nature 436.7052 (2005): 801-806.‏ the Mosers have discovered the grid cells. To show the ...
10
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1answer
129 views

What is the mechanism behind unihemispheric sleep in animals?

It is known that dolphins have the ability to sleep with only one half of their brain at a time. According to this popular science source: Dolphins sleep by resting one half of their brain at a ...
6
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2answers
70 views

Do the colour blind have a distinct visual cortex structure?

Studying the structure of the visual cortex, it seems there are many neural structures specifically dedicated to detecting and interpreting colour. For example, parvocellular cells are particularly ...
12
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3answers
412 views

What causes short-term dysphoria following intense pleasure?

I'm interested in the phenomenon of short term Dysphoria: Dysphoria is a state of feeling unwell or unhappy; a feeling of emotional and mental discomfort as a symptom of discontentment, ...
11
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2answers
470 views

Folding (wrinkles) in cortex: Why is surface area more important than volume?

When we look at the cortex of the brain, it has a folded structure. It is said that this is because this enables a greater number of neurons to exist, which is obviously advantageous. However, we ...
2
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1answer
110 views

How to filter noise in EEG data

I am a computer science student and I'm doing something for a psychology professor. We have EEG data from an experiment where a person was shown 140 images for 2 seconds each. We placed 64 electrodes ...
2
votes
2answers
86 views

Neurotransmitter control via biofeedback?

According to this thread, certain regions of the brain, and even some distributed activation patterns can be up/down regulated via bio-feedback. Is it possible in theory and is there any research ...
7
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1answer
117 views

Why does strobe lighting trigger seizures in photosensitive epilepsy?

Photosensitive epilepsy (PSE) is a form of epilepsy in which seizures are triggered by visual stimuli that form patterns in time or space, such as flashing lights, bold, regular patterns, or ...
3
votes
1answer
164 views

What causes lack of energy? The relative importance of testosterone versus emotional, genetic, and environmental factors

Some people assume that males lack of energy because of low testosterone. I would think that lack of energy could be due to esteem levels, emotional abuse, low self-worth, and even genetics to some ...
10
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3answers
163 views

What kinds of information can (and cannot) be extracted from connectome?

Several scientific projects are trying to map the connectome, such as The Human Connectome Project. The connectomes of other organisms, such as C. elegans, have been mapped already. Having an ...
3
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1answer
74 views

Where in the brain is meaning extracted from visual information?

I am looking into several systems for improving learning speeds and ran into a question I seem unable to answer on my own: When we read a word, it somehow gets converted into it's abstract meaning. ...
8
votes
1answer
113 views

Is there a report of a successfully EEG-Based Brain-Computer Interface (BCI) using image training?

Currently I am involved in constructing an EEG-Based BCI. The goal of the BCI is to control which light in a series of lightbulbs lights up. The plan is to use different images (i.e. a flower versus ...
2
votes
1answer
109 views

What is the biological reason behind disorganized thinking and disorganized behavior in thought disorders?

Having disorganized thinking is different for everyone. But, it is sometimes described as not being able to connect thoughts together. I am asking about disorganized thinking other than communication ...
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0answers
56 views

What is the result of an excess of dopamine?

I'm pretty familiar with the results of having not enough dopamine, though the reasons are not so clear to me. To get a better insight on the topic I'd like to know something about having too much ...
10
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2answers
176 views

Computational Model Linking Neural Activity to Behavior

A big question in neuroscience is how neural activity represents knowledge. We can use modelling to explore how different levels of neural activity- subthreshold currents, action potentials, local ...
3
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0answers
45 views

What neurotransmitters can be suppressed/promoted by tDCS

Transcranial Direct Current Stimulation (tDCS) has been shown to modify suppression in the visual cortex and GABA suppression in motor control. As of now, the exact neurobiological mechanism that ...
3
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0answers
57 views

Neuropharmacology and Simulation [closed]

I've been wondering whether neural simulations have had applications in (cognitive)neuropharmacological research already. One always reads about the promise of the technology in helping us cure ...
2
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0answers
32 views

Physiological mapping of frustration

What physiological changes are seen in the brain when a person is experiencing frustration? What effects do these changes have on learning? Optional background: I'm trying to figure out an ...
1
vote
1answer
68 views

Evolutionary motivation for the existence of pleasure

Firstly, I'd like to understand, what exactly is pleasure? If we presume we are streams of thoughts, thoughts being neurons activated in some pattern, and that basically anything what the conscience ...
3
votes
1answer
35 views

How do we localize pain?

I know that different points of the brain correspond to different point of the body. But how a sensory information reaches its correct corresponding area? For example, let say I put a pencil's ...
2
votes
1answer
28 views

What is the relationship between neurotransmitter release and resting potential in retinal bipolar cells?

Retinal bipolar cells are known to have resting potentials from which they can become more or less polarized. What I'm wondering is whether a bipolar cell's neurotransmitter-release rate is zero when ...
2
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0answers
26 views

Perforated patches: Can antibiotics used to induce holes in membrane produce perforations of differential size? [closed]

Perforated patches are a special type of patch clamping. I understand that it is sometimes preferred to whole-cell recordings because it prevents complete diffusion of the electrode solution into the ...
2
votes
1answer
97 views

What is runaway excitation?

Can someone give me a brief explanation of this term? Found it in a paper but there doesn't seem to be an explanation that is consistent out there to my knowledge.
3
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0answers
33 views

How does neurotransmitter distribution and usage vary thought the brain?

I understand that neurotransmitters are used to send signals between neurons in the brain and that some are used for rather specific functions. However, is the exact ...
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1answer
51 views

Prerequisite Request: Neurorobotics [closed]

For the newly emerging field, Neurorobotics. Can one list several highly recommended prerequisite courses prior to entering this field ? Except for classical machine learning, computational ...
2
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1answer
40 views

Is cortisol an effective measure of stress for pre and post task performance?

I have a teleoperation system and I want to see how much stress a person is under before during and after operating it. I thought cortisol would be a correlate of stress. Can I measure levels rapidly, ...