For questions about the biology of the nervous system, from a macroscopic to microscopic perspective.

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Explanatory gaps in the formation and propagation of action potentials

To my understanding, the steps of an action potential are as follows: The neuron is at rest--there is a negative charge (K ions) inside the cell, and a positive charge (Na ions) outside the cell. ...
2
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1answer
21 views

What is so “potential” about action potentials?

When an action potential is propagating through a neuron, it seems to me that the time for "potential of action" is over, and that we are now just in a state of "action". Why don't we just call action ...
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How does my spinal cord know to take reflexive action?

As in, how does my body know that a stove is not hot enough to warrant a reflex? Is it because there isn't a sudden electrical surge going through the nervous system?
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Do studies exist that can map specimens of neocortex to the functions they perform(ed) in vivo?

Much brain research has proposed that the brain (the neocortex, esp.) is set up in areas - an area for faces, an area for language, etc.. The experiments typically go 1) damage an area 2) observe ...
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1answer
24 views

How many dendrite connections vs axon terminals does a multipolar cerebral neuron have?

I find countless places that say neurons have tens of thousands of "connections" or "synapses" and one axon. Do neurons have tens of thousands of dendrite connections, and a few axon terminals; or a ...
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+50

How can we use EEG data to predict urge of smoking?

I am from Computer Sciences background. The problem which I want to target is to be able to successfully predict (to a degree) that a person is going to smoke in near future. I have a brainwave ...
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0answers
12 views

Role of white blood cell inside brain

Inside brain, Microglia cell is responsible for phagocytosis. It seems that brain can function properly without white blood cell. Also according to my research white blood can be hazardous to brain as ...
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1answer
4 views

Benefits of using more complicated neuron models in NEF models

The NEF allows you to use almost any neuron model as long as it has an equation for it's activity and it's spikes in some way. Usually, a simple leaky-integrate-fire (LIF) neuron model is used, but ...
3
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1answer
34 views

Can fMRI and EEG signals be generated from NEF models?

The basic function of the NEF is to map the outside world onto neurons, using the firing rates of the neurons. It also supports various neuron models. Have these firing rates been used to create EEG ...
2
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1answer
24 views

What is the difference between a biological and behaviorist perspective in psychology?

I was recently reading through a textbook and was unable to clearly identify the differences between the two due to a vague definition of both. Can someone provide an in-depth explanation of the two ...
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0answers
20 views

How can we analyse user behavior to predict urge of smoking?

The problem which I want to target is to be able to successfully predict (to a degree) that a person is going to smoke in near future. I want to look at the relationship between chemical reactions ...
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3answers
85 views

Can repetitive sports-related head injuries make a person senile many years later?

Would repetitive football injuries to the cranium show up decades later, causing symptoms resembling mild retardation, OCD, etc.? What is the best way to determine this in terms of imaging, testing, ...
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1answer
38 views

Regarding the mind and what it can affect

About the question 'Can the mind mind affect the brain?': Some responses are 'no' because the mind is a physical 'thing' or structure (if I read it correctly). Yet if the Mind is only a physical ...
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1answer
33 views

Visual acuity and offset stimuli

I'm currently setting up and experiment that utilises a visual search task that contains a circular array of target letters and a distractor that falls outside the circle. Obviously the further away ...
24
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3answers
14k views

Why would the brain flip the images perceived by your eyes?

The following is a common scientific statement, which you don't have to google long for to find: The eye views images upside-down in the manner of a camera lens, but our brains reinterpret this ...
21
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1answer
872 views

Have the abilities of John Lorber's patients with limited cortical mass been further evaluated in adulthood?

Short of minor lesions or infarcts, most high-functioning adults have an intact cerebral cortex. Yet, a surprising result published anecdotally in Science in 1980 caused a lot of scientists to take ...
3
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1answer
39 views

What are presynaptic puncta?

What are presynaptic puncta? And what makes them different from presynaptic terminals?
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2answers
258 views

What is the difference between pre-synaptic versus post-synaptic?

I am unclear as to the exact meaning of the terms pre-synaptic and post-synaptic. Specifically, do they refer to the same neuron, either transmitting or receiving, before and after the chemical ...
3
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1answer
61 views

Why do some people stutter only when they are nervous?

Background: I don't stutter at least not always. For example, if I be reading out a article to myself, It is sure that I will not stutter even that I am reading it out loud. The times when I do ...
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0answers
25 views

Are there parts of the brain which don't change over a lifetime?

We know that during our lifetime the brain develops new neural connections and also there is pruning of neural connections. These phenomena together are called neuroplasticity. Is there any research ...
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2answers
42 views

Grid cells : Between what is the correlation of autocorrelogram measured?

In their seminal paper Hafting, Torkel, et al. "Microstructure of a spatial map in the entorhinal cortex." Nature 436.7052 (2005): 801-806.‏ the Mosers have discovered the grid cells. To show the ...
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1answer
118 views

What is the mechanism behind unihemispheric sleep in animals?

It is known that dolphins have the ability to sleep with only one half of their brain at a time. According to this popular science source: Dolphins sleep by resting one half of their brain at a ...
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2answers
58 views

Do the colour blind have a distinct visual cortex structure?

Studying the structure of the visual cortex, it seems there are many neural structures specifically dedicated to detecting and interpreting colour. For example, parvocellular cells are particularly ...
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3answers
348 views

What causes short-term dysphoria following intense pleasure?

I'm interested in the phenomenon of short term Dysphoria: Dysphoria is a state of feeling unwell or unhappy; a feeling of emotional and mental discomfort as a symptom of discontentment, ...
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2answers
316 views

Folding (wrinkles) in cortex: Why is surface area more important than volume?

When we look at the cortex of the brain, it has a folded structure. It is said that this is because this enables a greater number of neurons to exist, which is obviously advantageous. However, we ...
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2answers
104 views

What is the neurobiological basis of the “inner voice” used for thought or reading?

I've recently experienced a number of hypnogogic near sleep states characterized by change in thinking (stage 1-2 sleep). I noticed that if I let go and get absorbed in the state, I can follow it. I ...
2
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1answer
47 views

How to filter noise in EEG data

I am a computer science student and I'm doing something for a psychology professor. We have EEG data from an experiment where a person was shown 140 images for 2 seconds each. We placed 64 electrodes ...
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2answers
74 views

Neurotransmitter control via biofeedback?

According to this thread, certain regions of the brain, and even some distributed activation patterns can be up/down regulated via bio-feedback. Is it possible in theory and is there any research ...
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0answers
17 views

What chemical or neurological mechanism causes the feeling of fulfillment?

We all know that someone can find intense pleasure in something without finding it fulfilling. But what causes our feeling of fulfillment? If I knew what it was, I could be more fulfilled and ...
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2answers
975 views

What are current neuronal explanations and models of 'consciousness'?

I would like to understand more about consciousness from a neuroscientific perspective. I have a limited understanding of it in the philosophical/psychological sense through lectures. Although it is ...
7
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1answer
113 views

Why does strobe lighting trigger seizures in photosensitive epilepsy?

Photosensitive epilepsy (PSE) is a form of epilepsy in which seizures are triggered by visual stimuli that form patterns in time or space, such as flashing lights, bold, regular patterns, or ...
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1answer
153 views

What causes lack of energy? The relative importance of testosterone versus emotional, genetic, and environmental factors

Some people assume that males lack of energy because of low testosterone. I would think that lack of energy could be due to esteem levels, emotional abuse, low self-worth, and even genetics to some ...
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3answers
156 views

What kinds of information can (and cannot) be extracted from connectome?

Several scientific projects are trying to map the connectome, such as The Human Connectome Project. The connectomes of other organisms, such as C. elegans, have been mapped already. Having an ...
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1answer
73 views

Where in the brain is meaning extracted from visual information?

I am looking into several systems for improving learning speeds and ran into a question I seem unable to answer on my own: When we read a word, it somehow gets converted into it's abstract meaning. ...
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1answer
108 views

Is there a report of a successfully EEG-Based Brain-Computer Interface (BCI) using image training?

Currently I am involved in constructing an EEG-Based BCI. The goal of the BCI is to control which light in a series of lightbulbs lights up. The plan is to use different images (i.e. a flower versus ...
2
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1answer
67 views

What is the biological reason behind disorganized thinking and disorganized behavior in thought disorders?

Having disorganized thinking is different for everyone. But, it is sometimes described as not being able to connect thoughts together. I am asking about disorganized thinking other than communication ...
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0answers
38 views

What is the result of an excess of dopamine?

I'm pretty familiar with the results of having not enough dopamine, though the reasons are not so clear to me. To get a better insight on the topic I'd like to know something about having too much ...
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2answers
165 views

Computational Model Linking Neural Activity to Behavior

A big question in neuroscience is how neural activity represents knowledge. We can use modelling to explore how different levels of neural activity- subthreshold currents, action potentials, local ...
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1answer
64 views

Is meaning-seeking behavior a biological optimization problem?

In short, I'm interested in cognitive, neuroscientific, biological and/or computational perspectives on what we vaguely refer to as meaning seeking. Of course, this is a large topic, but any ...
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0answers
37 views

What neurotransmitters can be suppressed/promoted by tDCS

Transcranial Direct Current Stimulation (tDCS) has been shown to modify suppression in the visual cortex and GABA suppression in motor control. As of now, the exact neurobiological mechanism that ...
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0answers
50 views

Neuropharmacology and Simulation

I've been wondering whether neural simulations have had applications in (cognitive)neuropharmacological research already. One always reads about the promise of the technology in helping us cure ...
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0answers
20 views

Physiological mapping of frustration

What physiological changes are seen in the brain when a person is experiencing frustration? What effects do these changes have on learning? Optional background: I'm trying to figure out an ...
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0answers
19 views

What is the neurobiological difference between Jungian Judging and Perceiving individual?

Jungian or Myers Briggs type indicator reserves the last letter of a 4 letter archetype to stand for Judging or Perceiving. Part of being a Judging type is punctuality - being on time, keeping ...
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1answer
65 views

Evolutionary motivation for the existence of pleasure

Firstly, I'd like to understand, what exactly is pleasure? If we presume we are streams of thoughts, thoughts being neurons activated in some pattern, and that basically anything what the conscience ...
3
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1answer
33 views

How do we localize pain?

I know that different points of the brain correspond to different point of the body. But how a sensory information reaches its correct corresponding area? For example, let say I put a pencil's ...
2
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1answer
28 views

What is the relationship between neurotransmitter release and resting potential in retinal bipolar cells?

Retinal bipolar cells are known to have resting potentials from which they can become more or less polarized. What I'm wondering is whether a bipolar cell's neurotransmitter-release rate is zero when ...
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0answers
22 views

Perforated patches: Can antibiotics used to induce holes in membrane produce perforations of differential size?

Perforated patches are a special type of patch clamping. I understand that it is sometimes preferred to whole-cell recordings because it prevents complete diffusion of the electrode solution into the ...
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0answers
25 views

What ways can STEM teaching change in USA to accommodate social needs of females?

Brizendine seems to point to the female brain as a handicap for STEM education due to the typical female's need for communication and sociability because of their estrogen needs eschew solitary ...
2
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1answer
57 views

What is runaway excitation?

Can someone give me a brief explanation of this term? Found it in a paper but there doesn't seem to be an explanation that is consistent out there to my knowledge.
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How does neurotransmitter distribution and usage vary thought the brain?

I understand that neurotransmitters are used to send signals between neurons in the brain and that some are used for rather specific functions. However, is the exact ...