For questions about the biology of the nervous system, from a macroscopic to microscopic perspective.

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Why do some people stutter only when they are nervous?

Background: I don't stutter at least not always. For example, if I be reading out a article to myself, It is sure that I will not stutter even that I am reading it out loud. The times when I do ...
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28 views

What research has been done examining the relationship between quantum physics and neural activity?

I have read that it has been observed that activity does occur within the brain in certain areas where there is no direct connection apparent (e.g., Quantum Mind on Wikipedia). See also this article ...
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2answers
202 views

Pre- vs post-synaptic

I am unclear as to the exact meaning of the terms pre-synaptic and post-synaptic. Specifically, do they refer to the same neuron, either transmitting or receiving, before and after the chemical ...
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2answers
44 views

Do the colour blind have a distinct visual cortex structure?

Studying the structure of the visual cortex, it seems there are many neural structures specifically dedicated to detecting and interpreting colour. For example, parvocellular cells are particularly ...
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1answer
41 views

How to filter noise in EEG data

I am a computer science student and I'm doing something for a psychology professor. We have EEG data from an experiment where a person was shown 140 images for 2 seconds each. We placed 64 electrodes ...
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14 views

What chemical or neurological mechanism causes the feeling of fulfillment?

We all know that someone can find intense pleasure in something without finding it fulfilling. But what causes our feeling of fulfillment? If I knew what it was, I could be more fulfilled and ...
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1answer
33 views

Grid cells : Between what is the correlation of autocorrelogram measured?

In their seminal paper Hafting, Torkel, et al. "Microstructure of a spatial map in the entorhinal cortex." Nature 436.7052 (2005): 801-806.‏ the Mosers have discovered the grid cells. To show the ...
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1answer
53 views

What is the biological reason behind disorganized thinking and disorganized behavior in thought disorders?

Having disorganized thinking is different for everyone. But, it is sometimes described as not being able to connect thoughts together. I am asking about disorganized thinking other than communication ...
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36 views

What is the result of an excess of dopamine?

I'm pretty familiar with the results of having not enough dopamine, though the reasons are not so clear to me. To get a better insight on the topic I'd like to know something about having too much ...
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36 views

What neurotransmitters can be suppressed/promoted by tDCS

Transcranial Direct Current Stimulation (tDCS) has been shown to modify suppression in the visual cortex and GABA suppression in motor control. As of now, the exact neurobiological mechanism that ...
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28 views

How to calculate the magnitude of the potential that will develop across the membrane?

If a cell is only permeable to K+ the inside of the cell is at 100mM KCL and outside at 1mM KCL What is the magnitude of the potential that will develop across the membrane?
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1answer
54 views

Is meaning-seeking behavior a biological optimization problem?

In short, I'm interested in cognitive, neuroscientific, biological and/or computational perspectives on what we vaguely refer to as meaning seeking. Of course, this is a large topic, but any ...
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Physiological mapping of frustration

What physiological changes are seen in the brain when a person is experiencing frustration? What effects do these changes have on learning? Optional background: I'm trying to figure out an ...
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1answer
102 views

Is there a report of a successfully EEG-Based Brain-Computer Interface (BCI) using image training?

Currently I am involved in constructing an EEG-Based BCI. The goal of the BCI is to control which light in a series of lightbulbs lights up. The plan is to use different images (i.e. a flower versus ...
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2answers
96 views

What is the neurobiological basis of the “inner voice” used for thought or reading?

I've recently experienced a number of hypnogogic near sleep states characterized by change in thinking (stage 1-2 sleep). I noticed that if I let go and get absorbed in the state, I can follow it. I ...
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0answers
18 views

What is the neurobiological difference between Jungian Judging and Perceiving individual?

Jungian or Myers Briggs type indicator reserves the last letter of a 4 letter archetype to stand for Judging or Perceiving. Part of being a Judging type is punctuality - being on time, keeping ...
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1answer
32 views

How do we localize pain?

I know that different points of the brain correspond to different point of the body. But how a sensory information reaches its correct corresponding area? For example, let say I put a pencil's ...
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0answers
24 views

What ways can STEM teaching change in USA to accommodate social needs of females?

Brizendine seems to point to the female brain as a handicap for STEM education due to the typical female's need for communication and sociability because of their estrogen needs eschew solitary ...
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1answer
50 views

What is runaway excitation?

Can someone give me a brief explanation of this term? Found it in a paper but there doesn't seem to be an explanation that is consistent out there to my knowledge.
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21 views

Perforated patches: Can antibiotics used to induce holes in membrane produce perforations of differential size?

Perforated patches are a special type of patch clamping. I understand that it is sometimes preferred to whole-cell recordings because it prevents complete diffusion of the electrode solution into the ...
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0answers
26 views

How does neurotransmitter distribution and usage vary thought the brain?

I understand that neurotransmitters are used to send signals between neurons in the brain and that some are used for rather specific functions. However, is the exact ...
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1answer
28 views

What is the relationship between neurotransmitter release and resting potential in retinal bipolar cells?

Retinal bipolar cells are known to have resting potentials from which they can become more or less polarized. What I'm wondering is whether a bipolar cell's neurotransmitter-release rate is zero when ...
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8 views

Determining the position of the calcium ion in the three dimensional space

Is it possible to determine the position of a single calcium ion or its population in the context of a three dimensional space with relatively good time frequency, say 1 Hz, taking into account ...
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1answer
38 views

Is cortisol an effective measure of stress for pre and post task performance?

I have a teleoperation system and I want to see how much stress a person is under before during and after operating it. I thought cortisol would be a correlate of stress. Can I measure levels rapidly, ...
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25 views

Do all humans have some amount of prions?

I understand that some humans can have prions that develop into neural diseases, but do all of us have at least some amount of prions in our bodies, and more specifically our brains?
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1answer
70 views

Brain after (electrical) blackout

I was wondering what happens if we lose all electrical impulses in our nervous system for a minimum amount of time. So first of all it is obvious that we will break together, as we are dead while we ...
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2answers
70 views

What background is required to understand the book “Principles of Neural Science”?

What is the necessary background to read this book and comprehend it? I've taken Calc I-II, Chem 1A and Bio 1A. Is this enough?
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1answer
58 views

Evolutionary motivation for the existence of pleasure

Firstly, I'd like to understand, what exactly is pleasure? If we presume we are streams of thoughts, thoughts being neurons activated in some pattern, and that basically anything what the conscience ...
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2answers
117 views

The psychology of nymphomania

So this is a question that requires maturity and discretion. I present it as an authentic point of research for a class I am taking. I understand the basic principles of mania, psychomania, and ...
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2answers
149 views

Why does a neuron choose to connect to another?

I have been reading about neuron creation, guidance cues and all sorts of highly complex mechanisms used to allow one neuron axon to extend or connect - but to what end? Why does one neuron end up ...
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50 views

Neuropharmacology and Simulation

I've been wondering whether neural simulations have had applications in (cognitive)neuropharmacological research already. One always reads about the promise of the technology in helping us cure ...
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2answers
194 views

Why is MATLAB so common in Neuroscience?

It is common knowledge that neuroscience -- particularly experimental neuroscience -- uses MATLAB more than any other programming language. I have always just taken this as a given, and pointed to ...
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1answer
35 views

How many action potentials from presynaptic neurons would be required to make a postsynaptic neuron fire?

I am looking for a rough estimation of the number of action potentials from other neurons required to cause a neuron to fire? I read here that a potential of ~ -55mv must be reached before an action ...
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2answers
53 views

Are there any serious neuroscientific theories of emotional valence?

Could anyone tell me if there are any serious neuroscientific mechanisms that have been proposed to explain how feelings of body states take on a positive or negative character (valence)? An example ...
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1answer
73 views

Where in the brain is meaning extracted from visual information?

I am looking into several systems for improving learning speeds and ran into a question I seem unable to answer on my own: When we read a word, it somehow gets converted into it's abstract meaning. ...
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1answer
41 views

Number of presynaptic inputs per cell in primary visual cortex

I have been digging in the literature lately, but I haven't found a nice answer with clear cut numbers (avg +- std) to this question: How many presynaptic inputs receives a pyramidal cell in primary ...
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36 views

Can microdialysis be made in Drosophila melanogaster?

Microdialysis is a common method to study the effects of drugs on specific mamal brains zones (mostly in rats), in order to study the it's interaction with the function of those specific areas that ...
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2answers
78 views

How does subjective experience arise from matter?

Forgive me for lacking rigor, but if what I know is correct, it is established that consciousness and other higher functions characteristic of humans are a consequence of our cortex, specifically ...
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1answer
48 views

How actively does your brain physically prune connections?

Is pruning defined as neural apoptosis or are connections (neural synapses) simply separated? At what rate, if known, does this occur in individuals (ages 18+)?
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2answers
78 views

Can repetitive sports-related head injuries make a person senile many years later?

Would repetitive football injuries to the cranium show up decades later, causing symptoms resembling mild retardation, OCD, etc.? What is the best way to determine this in terms of imaging, testing, ...
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0answers
57 views

Why is it easier to fall asleep in the dark?

I'm curious if there is any neurological mechanism that explains why falling asleep is easier in the dark. I recognize that this isn't true universally -- a phobia of darkness might make it easier to ...
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1answer
94 views

How many synapses in the average human brain?

Knowing there are 100,000,000,000 neurons in an average human brain, and 7,000 dendrites in each neuron, and neurons are connected to each other by dendrites and axon terminals, how many synapses are ...
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1answer
49 views

What was the quantified brain volume of Albert Einstein?

I have read articles stating that Albert Einstein had an average brain volume but couldn't find a specific measurement. I'm curious because the articles are all so ambiguous. He could have been on the ...
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2answers
28 views

Are there any programmes to identify modular “NeuroBricks”?

In synthetic biology, an organization called the BioBricks Foundation tries to identify modular biological components that are amenable to engineering design, and publishes them in the Registry of ...
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22 views

How do ligands bind to and release from receptors?

I'm wondering exactly how ligands bind to and release from receptors. Until recently I presumed ligands were attracted to receptors through electrostatic forces with no chemical interaction involved, ...
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1answer
28 views

What are the neurobiological factors associated with intelligence in animals?

For example, is there a well-defined relationship between "number of neurons in the cortex" and some measure of "intelligence" in animals? I'm familiar with the encephalization quotient - that is, ...
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5answers
339 views

Why do scientists say brains are faster than computers?

Supposing that neurons function similarly to transistors: A neuron able to fire $200$ times per second and transistors can be switched on and off more than $100,000,000,000$ times per second. Let's ...
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1answer
46 views

Prerequisite Request: Neurorobotics [closed]

For the newly emerging field, Neurorobotics. Can one list several highly recommended prerequisite courses prior to entering this field ? Except for classical machine learning, computational ...
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0answers
52 views

Trying to understand equations in Karl Friston article

I am trying to understand a neuroscience article by Karl Friston. In it he gives three equations that are, as I understand him, equivalent or inter-convertible and refer to both physical and Shannon ...
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1answer
166 views

OCD Motivation and Dopamine Motivation, is there a connection?

I understand that OCD is something that causes sufferers to perform irrational behavour consciously, I also understand that the motivation comes from performing the irrational behaviour/behaviours to ...