For questions about the biology of the nervous system, from a macroscopic to microscopic perspective.

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What is the role of Chloride (Cl- ions) in membrane potential?

This Membrane Potential article mentions only that that Cl- ion is used to model inhibitory GABA synapses. Does it have another role besides hyper-polarizing the cell due to inhibitory ...
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32 views

why is this stack exchange called 'cognitive sciences'? [migrated]

looking at the tags in this stack exchange, many are psychology and many are neuroscience. as somebody who does research in neuroscience, psychology, psychiatry, and neurology, it would have never ...
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Could ketosis be therapeutic for ADHD based on the neuro-energetic theory of attention?

I'm a complete neuroscience novice so please bear with me. One of the more interesting theories of the etiology of ADHD that I've read posits that the disorder may be one of neuroenergetics - the ...
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1answer
41 views

Unified Theory of the Human Brain [closed]

I'm a junior researcher(Life Sciences undergraduate) starting out in computational genetics of neuroscience, and I want to create a Unified Theory/Computational Model of the human brain and all its ...
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82 views

Lifelong avoidance coping style

Suppose someone has been using avoidance coping style for most of his or her life. The avoidance tendency is present in a broad range of situations, relatively constant through his or her life, not ...
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1answer
31 views

Are action potentials necessary for experience?

We know that, for example, during brain surgery, electrical stimulation in certain parts of the cortex is sufficient for experience, and result in reportable experiences in human subjects. We also ...
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91 views

Is there a biological limit for “amount” of happiness?

I have heard about neurotransmitters like dopamin and serotonin that are supposed to play a role in our feeling of happiness. I don't know how these chemicals works in our brain, but I am thinking ...
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32 views

What personality traits correlate with estrogen?

I'm looking for psychological traits that are proved to correlate with estrogen levels. Anything of specific behavior, attitudes, life styles, emotions, preferences, you name it. (I'm looking for ...
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How does oxygen deprivation affect neural activity?

It is increasingly common for someone to regain a heartbeat after a cardiac arrest. During the time that the person is without a heartbeat, and so without circulation, the brain is deprived of oxygen. ...
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What exactly is an astroglial calcium wave?

There are quite a few conflicting reports as to what stimulates them, how they propagate, whether they communicate intercellularly, and what they look like. The only consistent information I can ...
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2answers
66 views

Result of local stimulation in brain

What happens when we stimulate a brain in local regions? Some possibilities: We may trigger an action without the subject's awareness of the action; We can trigger an action in a subject, but we ...
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1answer
57 views

What is the neurophysiological mechanism behind double hearing?

A patient with sensorineural hearing loss can have the symptom of hearing "double" in the damaged ear. Not having a time-delayed echo, but hearing as if he (or other people) speak with "two voices" at ...
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4answers
138 views

If a human brain would be placed inside that of an animal: Could it talk?

Assumption: Animals can't talk 'human' because of their small(er) brain. Perhaps a strange thought, but I was really wondering: If we could place a human brain inside that of an animal: Would we be ...
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What are the highest ranked neuroscience journals that use double-blind review process?

In terms of impact factor (for a lack of a better proxy), what are the highest ranked neuroscience journals that use double-blind review process? I would be submitting a paper that combines ...
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34 views

Neurobiological perspective about dreams

I wanted to know what the difference is between dreaming and hallucinating from the neurobiological point of view. . Basically, I want to know what exactly the difference is in the neuro-chemistry of ...
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1answer
70 views

Why is the order of white/grey matter different in the brain and spinal cord?

In the brain proper, grey matter forms the outer layer of the brain, and white matter forms the inner layer. In the spine, this is reversed: white matter forms the outer layer of the spine, and grey ...
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66 views

Have any drugs been shown to increase the neuroplasticity of adult brains?

I read recently in the book "meet your happy chemicals" that the hormones of puberty are neurochemicals that cause your neurons to connect and myelinate more easily. If this is true have any studies ...
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1answer
39 views

Classical conditioning paradigm for hippocampal learning

I wanted to know what a suitable classical conditioning experiment would be to analyze learning and memory capabilities in rodent models with respect to hippocampal long-term potentiation (LTP). For ...
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1answer
263 views

Can stress or training influence the perception of time?

I have had this experience that I fell with my bike on an icy street. During the fall time seemed to slow down and I had an apparent age-long time window to stretch my hand and safely catch my fall. ...
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Neurobiology of addiction recovery

While addiction is one of the most studied topics in neurobiology, I don't see very much info on recovery. The information I have found is confusing. This one says striatal DAT bindings return to ...
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1answer
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Does an action potential abolish an excitatory postsynaptic potential?

From some sources, I've read that excitatory postsynaptic potentials (EPSPs) decay over time, which would imply that they aren't abolished by action potentials. However, other sources seem to indicate ...
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88 views

How similar are the brains of twins?

I am currently reading undergraduate essays on biological dysfunction and schizophrenia. The students put a lot of weight in the fact that studies of monozygotic twins show only a 50% rate of ...
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1answer
41 views

Is the weight of neural inputs in the human brain as central as it is for neurons in an artifical neural network?

As an example of an artificial neural net (ANN), a neural processing unit (NPU) is able to encode previous (learned) information by storing a weighted resistance for each input. Since ANN's are ...
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37 views

Is there a psychological/physical reason why sometimes your brain won't switch off when you want to sleep?

What is happening to the brain when you are trying to sleep but can't? I think this is a fairly common phenomena. In a situation when you are tired and ready to sleep, why can't you switch off? It's ...
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Is movement/activity level related to serotonin availability or reuptake rates in the brain?

I'm aware of this research article that explores the relationship between motion and serotonin systems: 5-HT and motor control: a hypothesis. Based on the article above, it seems to me that a "very ...
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1answer
69 views

What's the difference between executive functions and cognitive control?

I suspect that the difference between these terms may vary from researcher to researcher, since the wikipedia page treats them as synonymous. What's the difference between executive functioning and ...
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126 views

Are the center surround receptive fields learnt or inherited?

I know that neurons higher in visual pathways can learn their receptive fields after birth, but what about the connections between bipolar cells and Amacarine cells which form center/surround on/off ...
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1answer
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Why does anger “clouds the mind”?

There are a lot of anecdotes on frustration and anger inhibiting judgement and problem solving. Examples include "anger clouds the mind" in pop culture or in programming - "if you're stuck on a ...
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Psychological problem with glasses and hats on head? [closed]

I knew a kid who, when they was little, they would have attacks when a relative removed their glasses. She would sometimes do it on purpose in front of them and they would have emotional outbursts ...
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1answer
49 views

How does Parkinson's disease result in tremors?

From what I understand, Parkinson's disease is caused by the death of dopamine producing cells in the substantia nigra, however I don't understand how that causses the symptoms of Parkinson's. I am ...
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31 views

How does de-myelination occur in multiple sclerosis? [closed]

From what I understand, only the oligodendrocytes are affected in multiple sclerosis, and they are attacked by T cells which cross the blood-brain barrier. This leads me to two questions: How is the ...
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0answers
85 views

What are the brain regions related to tinnitus shown in this figure?

I am interested in learning about the neural mechanisms behind tinnitus, and was wondering if someone could help me to name the parts of the brain on this image that show increased activity in ...
5
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1answer
75 views

Difference in frequencies of mistakes between use of left-right vs. up-down

I have no hard data, but from my personal experience in people specifying right or left directions (similarly east or west) and up or down (north or south, top or bottom), people frequently make ...
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61 views

Can positive self-affirmation improve mood?

Most people get "depressed" every now and then - nothing serious, but people sometimes feel down. I am wondering if positive self-affirmation can make you happier by physically increasing the ...
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Colorado Boulder study about brain morphometric measures of Cannabis users methodologically weak?

I'm relating to this study: http://www.jneurosci.org/content/35/4/1505.short The researchers found no differences in subcortical brain structures for daily Cannabis users vs. controls. However the ...
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Are there mental reflexes?

Similar to knee-jerk or withdrawal, are there any innate reflexes in cognition? Are they based on personality, or are there any that are universal?
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2answers
102 views

Is there a difference between hearing and decoding the sound?

I presume that deafness is the inability of hearing any sounds. And I presume that it's also possible to be less able to decode (and translate to a meaningful message) what others speak [happens a lot ...
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1answer
82 views

What are the neurobiological factors related to depression?

While it is agreed that neurotransmitters aren't the primary "cause" of depression, what other factors are a part of this mental illness that focus on the neurobiological aspects of it?
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Why does the unilateral 6-OHDA lesion Parkinson's model cause ipsilateral rotations?

As far as I understand, the loss of dopaminergic neurons should hinder movement in the contralateral side of the body, resulting in contralateral rotations when the animal tries to move forward.
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What are the smallest neurons ever identified? [closed]

What are the smallest neurons ever measured? I'm happy with any superlatives, such as the thinnest axons or dendrites, smallest somata etc. Thank you :)
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Smallest neurons [duplicate]

What are the smallest measured neurons ever measured in the animal kingdom? I did some research but couldn't find a definite answer. In us, it's the cerebellar granule cell as far as I know, but I'm ...
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2answers
74 views

Activity in a brain region and additional blood requirement: What is the causal relation?

May I know causal dependence of the blood flow in the brain? How it is determined by the brain that particular brain region requires additional blood?
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1answer
49 views

Why is the order of brainwaves not labelled “alphabetically”?

The brainwave - frequency breakdown is as follows: Delta wave – (0.1 – 3 Hz) Theta wave – (4 – 7 Hz) Alpha wave – (8 – 15 Hz) Mu wave – (7.5 – 12.5 Hz) SMR wave – (12.5 – 15.5 Hz) Beta wave – (16 – ...
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1answer
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How does my spinal cord know to take reflexive action?

As in, how does my body know that a stove is not hot enough to warrant a reflex? Is it because there isn't a sudden electrical surge going through the nervous system?
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2answers
116 views

Explanatory gaps in the formation and propagation of action potentials

To my understanding, the steps of an action potential are as follows: The neuron is at rest--there is a negative charge (K ions) inside the cell, and a positive charge (Na ions) outside the cell. ...
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1answer
66 views

What is so “potential” about action potentials?

When an action potential is propagating through a neuron, it seems to me that the time for "potential of action" is over, and that we are now just in a state of "action". Why don't we just call action ...
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Do studies exist that can map specimens of neocortex to the functions they perform(ed) in vivo?

Much brain research has proposed that the brain (the neocortex, esp.) is set up in areas - an area for faces, an area for language, etc.. The experiments typically go 1) damage an area 2) observe ...
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1answer
85 views

How many dendrite connections vs axon terminals does a multipolar cerebral neuron have?

I find countless places that say neurons have tens of thousands of "connections" or "synapses" and one axon. Do neurons have tens of thousands of dendrite connections, and a few axon terminals; or a ...
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1answer
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Can fMRI and EEG signals be generated from NEF models?

The basic function of the NEF is to map the outside world onto neurons, using the firing rates of the neurons. It also supports various neuron models. Have these firing rates been used to create EEG ...
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1answer
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Benefits of using more complicated neuron models in NEF models

The NEF allows you to use almost any neuron model as long as it has an equation for it's activity and it's spikes in some way. Usually, a simple leaky-integrate-fire (LIF) neuron model is used, but ...