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The Blue Brain project led by Henry Markram focused on simulating cortical columns under the idea they form basic processing units of the brain/cognitive function.

What does a cortical column do?

I am looking for (synopses) of mathematical, conceptual, & scientific models. What is a leading theory, what is the evidence for it, etc?

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Vernon Mountcastle was instrumental in the discovery of the cortical column. I will elaborate a bit more later, but some of his older papers are probably freely available online. –  Chuck Sherrington Feb 13 at 23:47
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How about starting with en.wikipedia.org/wiki/Cortical_column ? –  H.Muster Feb 14 at 7:44
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@H.Muster I was actually going to make the same comment, but I was surprised by how uninformative that wikipedia article and the discussion here were. In general, a quick Google search doesn't reveal an obvious definitive resource, either. Hence, it might be good to provide a canonical answer here if jonsca has time. Of course, I do wish that the OP would focus the question more, since it is pretty vague. –  Artem Kaznatcheev Feb 14 at 17:35
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Here's an example of a much better focused question on bio.SE. –  Artem Kaznatcheev Feb 14 at 17:38
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the other question seems to be focused on mere anatomy –  vzn Feb 14 at 17:58

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I have worked with the theory that the column is the binary unit involved in all cortical processing and memory for many years. Articles are available at my profile page (Robert Moss) at researchgate.net and academia.com. The first article was published in 2006 with an update in 2012. I have published several non-peer-reviewed, more easily understandable articles that are also posted at those sites. One major paper is under review that explains the possible microcircuitry of dynamically formed columns. Check out AIMS Neuroscience for upcoming theroetical articles.

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thx can you post a ref for a single survey article to start with –  vzn May 9 at 14:59

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