The plot of the movie Final Analysis revolves around a murder committed by a person diagnosed with Pathological Intoxication.
The following study confirms the:
probable existence of a discrete syndrome of pathological reaction to alcohol without reference to the amount of alcohol consumed.
The Diagnosis of Pathological Intoxication
Barry M. Maletzky
Volume 37, 1976 > Issue 09: September 1976
Journal of Studies on Alcohol and Drugs.
However there are doubts as raised by the following article.
The existence of pathological intoxication as an entity must remain in doubt unless the disorder can be reproduced under controlled conditions.
Pathological intoxication--is there such an entity?
J Clin Psychiatry. 1979 Oct;40(10):424-6.
I can see other conflicting articles; What is the latest position on Pathological Intoxication?