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I found this clip about dopamine deficiency.

...[P]eople with low dopamine activity may be more prone to addiction.

Is the reverse also true? Does susceptibility to addiction (genetic, etc.) have an effect on the likelihood that one may have a dopamine deficit?

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up vote 2 down vote accepted

It seems that genetic plays significant roles in dopamine addiction: http://www.ncbi.nlm.nih.gov/pubmed/22350797

And also a study of "born-addicts": http://www.addictscience.com/genetics-d2/

But also it is connected to ADHD studies. It is well known that people with ADHD are vulnerable to addiction. They think it is because reward deficiency system: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626918/

When ADHD patients get medicine based on dopamine or amphetamine their attention improves.

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